Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2C | P18825 | 1/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.35 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.35 |
| ▸ | CPB2 | Q96IY4 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | KIF11 | P52732 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | GSR | P00390 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9716633 | 1.00 | ADRA2C (0.38) | ADRA2CF2KDM4EMAPTHIF1A | |
| SCHEMBL9716829 | 0.95 | F2 (0.40) | ADRA2CF2KDM4EMAPTHIF1A | |
| SCHEMBL9716819 | 0.95 | F2 (0.40) | ADRA2CF2KDM4EMAPTHIF1A | |
| SCHEMBL9716674 | 0.88 | SLC7A5 (0.39) | ADRA2CF2MAPTHIF1ACPB2 | |
| SCHEMBL9716685 | 0.88 | SLC7A5 (0.39) | ADRA2CF2MAPTHIF1ACPB2 | |
| SCHEMBL15484293 | 0.88 | ADRA2C (0.50) | ADRA2CF2CPB2TSHRHTR2A | |
| SCHEMBL9716684 | 0.88 | ADRA2C (0.50) | ADRA2CF2CPB2TSHRHTR2A | |
| SCHEMBL9716679 | 0.88 | ADRA2C (0.50) | ADRA2CF2CPB2TSHRHTR2A | |
| SCHEMBL9716737 | 0.87 | ALDH1A1 (0.38) | ADRA2CF2MAPTNPC1RAB9A | |
| SCHEMBL9716619 | 0.84 | F2 (0.40) | ADRA2CF2HIF1ACPB2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0178911-B1 | COMPOSITION CONTAINING A PENEM OR CARBAPENEM ANTIBIOTIC | SANKYO COMPANY LIMITED (JP) | 1992-01-22 | — | — | EP | disclosed |
| EP-0178911-A2 | Composition containing a penem or carbapenem antibiotic | SANKYO COMPANY LIMITED (JP) | 1986-04-23 | — | — | EP | disclosed |