Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 1/20 | 0.59 |
| ▸ | HTR7 | P34969 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.44 |
| ▸ | DRD1 | P21728 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9716870 | 0.84 | L3MBTL1 (0.55) | NPC1RAB9AL3MBTL1PTPN1LMNA | |
| SCHEMBL6701558 | 0.83 | L3MBTL1 (0.71) | NPC1RAB9AHTR7L3MBTL1PTPN1 | |
| SCHEMBL10248323 | 0.82 | NPC1 (0.69) | NPC1RAB9AHTR7L3MBTL1PTPN1 | |
| SCHEMBL3822016 | 0.82 | NPC1 (0.69) | NPC1RAB9AHTR7L3MBTL1PTPN1 | |
| SCHEMBL17032601 | 0.79 | NPC1 (0.62) | NPC1RAB9AHTR7PTPN1TSHR | |
| SCHEMBL9680520 | 0.76 | NPC1 (0.91) | NPC1RAB9AHTR7L3MBTL1PTPN1 | |
| SCHEMBL4897835 | 0.75 | NPC1 (0.62) | NPC1RAB9AHTR7PTPN1KMT2A | |
| SCHEMBL1040636 | 0.74 | NPC1 (0.87) | NPC1RAB9AHTR7L3MBTL1PTPN1 | |
| SCHEMBL9680984 | 0.74 | NPC1 (0.87) | NPC1RAB9AHTR7L3MBTL1PTPN1 | |
| SCHEMBL3424496 | 0.74 | NPC1 (0.87) | NPC1RAB9AHTR7L3MBTL1PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5089529-A | Antiarrhythmia agents | NIPPON SHINYAKU CO., LTD. (JP) | 1992-02-18 | — | — | US | disclosed |