Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.69 |
| ▸ | RAB9A | P51151 | 1/20 | 0.69 |
| ▸ | HTR7 | P34969 | 1/20 | 0.66 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.55 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | GSR | P00390 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | THRA | P10827 | 2/20 | 0.49 |
| ▸ | THRB | P10828 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.49 |
| ▸ | HTR1A | P08908 | 1/20 | 0.49 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.49 |
| ▸ | DRD1 | P21728 | 1/20 | 0.49 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.49 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.49 |
| ▸ | DRD3 | P35462 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9670891 | 0.91 | GSR (0.58) | NPC1RAB9AHTR7GSRTHRA | |
| SCHEMBL4897835 | 0.89 | NPC1 (0.62) | NPC1RAB9AHTR7GSRSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL4384839 | 0.87 | GSR (0.63) | NPC1RAB9AHTR7L3MBTL1TSHR | |
| SCHEMBL9148552 | 0.84 | THRA (0.59) | NPC1RAB9AHTR7L3MBTL1THRA | |
| SCHEMBL10440428 | 0.84 | NPC1 (0.68) | NPC1RAB9AL3MBTL1GSRKDM4E | |
| SCHEMBL6701558 | 0.83 | L3MBTL1 (0.71) | NPC1RAB9AHTR7L3MBTL1TSHR | |
| SCHEMBL9680520 | 0.82 | NPC1 (0.91) | NPC1RAB9AHTR7L3MBTL1TSHR | |
| SCHEMBL9716696 | 0.82 | NPC1 (0.59) | NPC1RAB9AHTR7L3MBTL1SLC6A4 | |
| SCHEMBL5954501 | 0.82 | GAA (0.59) | NPC1RAB9AL3MBTL1TSHRGSR | |
| SCHEMBL6824194 | 0.81 | KMT2A (0.67) | NPC1RAB9AL3MBTL1GSRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1173431-B2 | METHOD FOR THE PREPARATION OF CITALOPRAM | LUNDBECK & CO AS H (DK) | 2009-08-26 | — | — | EP | claimed |
| US-6849749-B2 | Method for the preparation of citalopram | H. LUNDBECK A/S (DK) | 2005-02-01 | — | — | US | claimed |
| EP-1173431-B1 | METHOD FOR THE PREPARATION OF CITALOPRAM | LUNDBECK & CO AS H (DK) | 2003-04-16 | — | — | EP | claimed |
| US-20020040153-A1 | Method for the preparation of citalopram | H. LUNDBECK A/S (DK) | 2002-04-04 | — | — | US | claimed |
| CN-111533662-B | Synthesis method of citalopram intermediate | 福建海西新药创制有限公司 | 2022-08-23 | — | — | CN | disclosed |
| CN-111533662-A | Synthesis method of citalopram intermediate | 福建海西新药创制有限公司 | 2020-08-14 | — | — | CN | disclosed |
| CN-101133041-B | Piperazino based multi-functional photoinitiators | SUN CHEMICAL LTD | 2012-06-20 | — | — | CN | disclosed |
| EP-1173431-B2 | METHOD FOR THE PREPARATION OF CITALOPRAM | LUNDBECK & CO AS H (DK) | 2009-08-26 | — | — | EP | disclosed |
| CN-101133041-A | Piperazino based multi-functional photoinitiators | SUN CHEMICAL LTD (GB) | 2008-02-27 | — | — | CN | disclosed |
| US-7030252-B2 | Method for the preparation of citalopram | H. LUNDBECK A/S (DK) | 2006-04-18 | — | — | US | disclosed |
| US-20050124817-A1 | Method for the preparation of citalopram | PETERSEN HANS (DK) | 2005-06-09 | — | — | US | disclosed |
| US-6849749-B2 | Method for the preparation of citalopram | H. LUNDBECK A/S (DK) | 2005-02-01 | — | — | US | disclosed |
| EP-1173431-B1 | METHOD FOR THE PREPARATION OF CITALOPRAM | LUNDBECK & CO AS H (DK) | 2003-04-16 | — | — | EP | disclosed |
| US-20020040153-A1 | Method for the preparation of citalopram | H. LUNDBECK A/S (DK) | 2002-04-04 | — | — | US | disclosed |
| US-5534629-A | PHOTOPOLYMERIZATION OF PIGMENTED SYSTEMS, INKS | CIBA-GEIGY CORPORATION (US) | 1996-07-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050124817-A1 | Method for the preparation of citalopram | MAOB, MAOA, TPH1 | NPC1 2943/4885RAB9A 3001/4885HTR7 31/4885 |
| US-20020040153-A1 | Method for the preparation of citalopram | TPH1, MAOB, MAOA | NPC1 2469/4885RAB9A 3370/4885HTR7 35/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.