Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.55 |
| ▸ | BCL2 | P10415 | 6/20 | 0.55 |
| ▸ | CHRM4 | P08173 | 5/20 | 0.52 |
| ▸ | CHRM5 | P08912 | 5/20 | 0.52 |
| ▸ | CHRM3 | P20309 | 5/20 | 0.52 |
| ▸ | CHRM2 | P08172 | 4/20 | 0.52 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | KIF11 | P52732 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9716709 | 0.94 | BCL2 (0.50) | SIGMAR1BCL2CHRM4CHRM5CHRM3 | |
| SCHEMBL9716801 | 0.93 | SIGMAR1 (0.62) | SIGMAR1BCL2CHRM4CHRM5CHRM3 | |
| Hydrochloric Acid SCHEMBL9716825 | 0.91 | CHRM4 (0.62) | SIGMAR1BCL2CHRM4CHRM5CHRM3 | |
| Maleic Acid SCHEMBL9716787 | 0.84 | SIGMAR1 (0.52) | SIGMAR1BCL2CHRM4CHRM5CHRM3 | |
| Fumaric Acid SCHEMBL9716792 | 0.84 | SIGMAR1 (0.52) | SIGMAR1BCL2CHRM4CHRM5CHRM3 | |
| SCHEMBL9716867 | 0.82 | BCL2 (0.50) | SIGMAR1BCL2CHRM4CHRM5CHRM3 | |
| Maleic Acid SCHEMBL9716839 | 0.81 | BCL2 (0.47) | SIGMAR1BCL2CHRM4CHRM5CHRM3 | |
| Fumaric Acid SCHEMBL9716852 | 0.81 | BCL2 (0.47) | SIGMAR1BCL2CHRM4CHRM5CHRM3 | |
| SCHEMBL9716800 | 0.81 | BCL2 (0.49) | SIGMAR1BCL2CHRM4CHRM5CHRM3 | |
| Maleic Acid SCHEMBL9716806 | 0.80 | BCL2 (0.46) | SIGMAR1BCL2CHRM4CHRM5CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5089529-A | Antiarrhythmia agents | NIPPON SHINYAKU CO., LTD. (JP) | 1992-02-18 | — | — | US | claimed |
| US-5089529-A | Antiarrhythmia agents | NIPPON SHINYAKU CO., LTD. (JP) | 1992-02-18 | — | — | US | disclosed |