Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2 | P10415 | 3/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.43 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.43 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | TYR | P14679 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | MLYCD | O95822 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9716709 | 0.88 | BCL2 (0.50) | BCL2SIGMAR1CHRM2CHRM4CHRM5 | |
| SCHEMBL9716800 | 0.86 | BCL2 (0.49) | BCL2SIGMAR1CHRM2CHRM4CHRM5 | |
| SCHEMBL9716801 | 0.86 | SIGMAR1 (0.62) | BCL2SIGMAR1CHRM2CHRM4CHRM5 | |
| SCHEMBL9716799 | 0.85 | BCL2 (0.48) | BCL2SIGMAR1CHRM2CHRM4CHRM5 | |
| Hydrochloric Acid SCHEMBL9716825 | 0.84 | CHRM4 (0.62) | BCL2SIGMAR1CHRM2CHRM4CHRM5 | |
| SCHEMBL9716774 | 0.82 | SIGMAR1 (0.55) | BCL2SIGMAR1CHRM2CHRM4CHRM5 | |
| SCHEMBL9716879 | 0.81 | BCL2 (0.44) | BCL2SIGMAR1CHRM2CHRM4CHRM5 | |
| Maleic Acid SCHEMBL9716757 | 0.78 | BCL2 (0.42) | BCL2SIGMAR1CHRM2CHRM4CHRM5 | |
| Fumaric Acid SCHEMBL9716767 | 0.78 | BCL2 (0.42) | BCL2SIGMAR1CHRM2CHRM4CHRM5 | |
| Maleic Acid SCHEMBL9716787 | 0.77 | SIGMAR1 (0.52) | BCL2SIGMAR1CHRM2CHRM4CHRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5089529-A | Antiarrhythmia agents | NIPPON SHINYAKU CO., LTD. (JP) | 1992-02-18 | — | — | US | claimed |
| US-5089529-A | Antiarrhythmia agents | NIPPON SHINYAKU CO., LTD. (JP) | 1992-02-18 | — | — | US | disclosed |