Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 20/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29557925 | 1.00 | REN (0.54) | REN | |
| SCHEMBL7327962 | 0.82 | REN (0.53) | REN | |
| SCHEMBL7323412 | 0.82 | REN (0.53) | REN | |
| SCHEMBL7327958 | 0.82 | REN (0.53) | REN | |
| SCHEMBL7323402 | 0.82 | REN (0.53) | REN | |
| SCHEMBL7277185 | 0.75 | REN (0.75) | REN | |
| SCHEMBL7277190 | 0.75 | REN (0.75) | REN | |
| SCHEMBL9220087 | 0.75 | REN (0.75) | REN | |
| SCHEMBL7275350 | 0.75 | REN (0.75) | REN | |
| SCHEMBL7323175 | 0.75 | REN (0.62) | REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0498361-A2 | Combination of an angiotensin II antagonist or renin inhibitor with a neutral endopeptidase inhibitor | SCHERING CORPORATION (US) | 1992-08-12 | — | — | EP | disclosed |