Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 5/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.42 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.41 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.39 |
| ▸ | PPARG | P37231 | 7/20 | 0.39 |
| ▸ | PPARD | Q03181 | 7/20 | 0.39 |
| ▸ | PPARA | Q07869 | 7/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TLR2 | O60603 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | FABP4 | P15090 | 2/20 | 0.39 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1712696 | 0.86 | — | — | |
| SCHEMBL9825916 | 0.84 | KDM4C (0.34) | ALOX15KMT2A | |
| SCHEMBL12450514 | 0.76 | LMNA (0.48) | LMNASLC22A6TSHRNFKB1PMP22 | |
| SCHEMBL27684562 | 0.76 | KDM4A (0.52) | LMNASLC22A6TSHRNFKB1PMP22 | |
| SCHEMBL11771846 | 0.75 | KDM4C (0.57) | LMNASLC22A6TSHRNFKB1PMP22 | |
| SCHEMBL145724 | 0.75 | — | — | |
| SCHEMBL16792232 | 0.74 | CAMK2A (0.46) | LMNASLC22A6TSHRNFKB1PMP22 | |
| SCHEMBL739305 | 0.73 | — | — | |
| Hydrochloric Acid SCHEMBL4520823 | 0.73 | KDM4A (0.59) | LMNASLC22A6TSHRNFKB1PMP22 | |
| Methane SCHEMBL28698626 | 0.73 | KDM4A (0.53) | LMNASLC22A6TSHRNFKB1PMP22 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5106951-A | Antineoplastic anthracyline agents intercalated with two aromatic side chains or an oligopeptide and covalently attached to an antibody | NEORX CORPORATION (US) | 1992-04-21 | — | — | US | disclosed |
| EP-0329184-A2 | Antimers and antimeric conjugation | NEORX CORPORATION (US) | 1989-08-23 | — | — | EP | disclosed |