Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 14/20 | 0.34 |
| ▸ | KDM5A | P29375 | 4/20 | 0.34 |
| ▸ | PHF8 | Q9UPP1 | 3/20 | 0.33 |
| ▸ | KDM2A | Q9Y2K7 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | KDM6B | O15054 | 1/20 | 0.33 |
| ▸ | KDM5C | P41229 | 1/20 | 0.33 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.33 |
| ▸ | KDM4A | O75164 | 11/20 | 0.33 |
| ▸ | KDM7A | Q6ZMT4 | 2/20 | 0.33 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9716849 | 0.84 | LMNA (0.43) | ALOX15KMT2A | |
| SCHEMBL28262828 | 0.79 | KDM4C (0.48) | KDM4CKDM5APHF8KDM2AKDM4E | |
| SCHEMBL1712696 | 0.79 | — | — | |
| Dimethylformamide SCHEMBL27908649 | 0.77 | HAO1 (0.44) | KDM4CKDM5AHAO1ALOX15MAPT | |
| SCHEMBL9418710 | 0.71 | SLC22A6 (0.53) | PHF8KDM2AKDM4EKDM6BKDM5C | |
| SCHEMBL9185822 | 0.71 | LMNA (0.53) | PHF8KDM2AKDM4EKDM6BKDM5C | |
| SCHEMBL22290977 | 0.71 | KDM4E (0.40) | KDM4EALOX15KMT2A | |
| SCHEMBL21696930 | 0.69 | LMNA (0.38) | KDM4CKDM5APHF8KDM2AKDM4A | |
| SCHEMBL8751902 | 0.69 | TSHR (0.56) | HAO1ALOX15MAPTKMT2A | |
| SCHEMBL6265240 | 0.69 | TSHR (0.56) | HAO1ALOX15MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0302980-B1 | 1,4-DIHYDROPYRIDINES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS MEDICAMENTS | LABORATORIOS DELAGRANGE S.A. (ES) | 1991-03-13 | — | — | EP | claimed |