Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.61 |
| ▸ | MAPT | P10636 | 5/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.61 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.61 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.61 |
| ▸ | HTR2B | P41595 | 1/20 | 0.61 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.50 |
| ▸ | TFEB | P19484 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | AR | P10275 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29857458 | 0.90 | LMNA (0.60) | LMNAMAPTMEN1NR1I2CHRM2 | |
| SCHEMBL10383307 | 0.87 | KDM4E (0.65) | LMNAMAPTMEN1NR1I2CHRM2 | |
| SCHEMBL4331860 | 0.87 | PTGER1 (0.59) | LMNAMAPTMEN1NR1I2CHRM2 | |
| SCHEMBL9716933 | 0.87 | PTGER1 (0.59) | LMNAMAPTMEN1NR1I2CHRM2 | |
| SCHEMBL9716995 | 0.87 | PTGER1 (0.59) | LMNAMAPTMEN1NR1I2CHRM2 | |
| SCHEMBL9717006 | 0.87 | PTGER1 (0.59) | LMNAMAPTMEN1NR1I2CHRM2 | |
| SCHEMBL242465 | 0.87 | PTGER1 (0.59) | LMNAMAPTMEN1NR1I2CHRM2 | |
| SCHEMBL9402733 | 0.87 | PTGER1 (0.59) | LMNAMAPTMEN1NR1I2CHRM2 | |
| SCHEMBL8092292 | 0.87 | PTGER1 (0.59) | LMNAMAPTMEN1NR1I2CHRM2 | |
| SCHEMBL4331862 | 0.87 | PTGER1 (0.59) | LMNAMAPTMEN1NR1I2CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992009561-A1 | NEW AMIDE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-06-11 | — | — | WO | disclosed |