Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.72 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.72 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.62 |
| ▸ | PKM | P14618 | 1/20 | 0.61 |
| ▸ | TLR4 | O00206 | 1/20 | 0.56 |
| ▸ | TLR2 | O60603 | 1/20 | 0.56 |
| ▸ | LTB4R | Q15722 | 2/20 | 0.54 |
| ▸ | PLA2G4B | P0C869 | 3/20 | 0.54 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | BCHE | P06276 | 2/20 | 0.50 |
| ▸ | ACHE | P22303 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7969956 | 1.00 | KDM4E (0.72) | KDM4EALDH1A1SMN1; SMN2CYSLTR2PKM | |
| SCHEMBL9717025 | 1.00 | KDM4E (0.72) | KDM4EALDH1A1SMN1; SMN2CYSLTR2PKM | |
| SCHEMBL7970157 | 1.00 | KDM4E (0.72) | KDM4EALDH1A1SMN1; SMN2CYSLTR2PKM | |
| SCHEMBL7969953 | 1.00 | KDM4E (0.72) | KDM4EALDH1A1SMN1; SMN2CYSLTR2PKM | |
| SCHEMBL7970153 | 1.00 | KDM4E (0.72) | KDM4EALDH1A1SMN1; SMN2CYSLTR2PKM | |
| SCHEMBL9015708 | 1.00 | KDM4E (0.72) | KDM4EALDH1A1SMN1; SMN2CYSLTR2PKM | |
| SCHEMBL8784206 | 0.94 | KDM4E (0.76) | KDM4EALDH1A1SMN1; SMN2CYSLTR2PKM | |
| SCHEMBL8784209 | 0.94 | KDM4E (0.76) | KDM4EALDH1A1SMN1; SMN2CYSLTR2PKM | |
| SCHEMBL28397201 | 0.90 | KDM4E (0.78) | KDM4EALDH1A1SMN1; SMN2CYSLTR2PKM | |
| SCHEMBL28397202 | 0.90 | KDM4E (0.78) | KDM4EALDH1A1SMN1; SMN2CYSLTR2PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992009561-A1 | NEW AMIDE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-06-11 | — | — | WO | disclosed |