Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | HPGD | P15428 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.43 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.42 |
| ▸ | FHIT | P49789 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11563077 | 0.90 | MAPT (0.52) | MAPTALDH1A1HPGDSMN1; SMN2GAA | |
| SCHEMBL9157297 | 0.82 | ALDH1A1 (0.47) | MAPTALDH1A1HPGDSMN1; SMN2GAA | |
| SCHEMBL11862970 | 0.79 | GAA (0.45) | MAPTALDH1A1HPGDSMN1; SMN2GAA | |
| SCHEMBL11862965 | 0.77 | NR1H2 (0.43) | MAPTALDH1A1HPGDSMN1; SMN2GAA | |
| SCHEMBL9717190 | 0.77 | SMN1; SMN2 (0.41) | MAPTALDH1A1HPGDSMN1; SMN2GAA | |
| SCHEMBL9717124 | 0.76 | TSHR (0.40) | MAPTALDH1A1HPGDGAAHTT | |
| SCHEMBL9535859 | 0.76 | ALDH1A1 (0.38) | ALDH1A1HPGDCA1CA2HSD17B10 | |
| SCHEMBL28885275 | 0.76 | CYP1A2 (0.45) | MAPTALDH1A1HPGDSMN1; SMN2GAA | |
| SCHEMBL7901277 | 0.75 | ALDH1A1 (0.50) | MAPTALDH1A1HSD17B10TSHRCYP3A4 | |
| SCHEMBL7901269 | 0.75 | ALDH1A1 (0.50) | MAPTALDH1A1HSD17B10TSHRCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5162405-A | Single-functional and mixtures of multi-functional oligomeric performance additive compositions and their uses | ELF ATOCHEM NORTH AMERICA, INC. (US) | 1992-11-10 | — | — | US | disclosed |
| US-5013777-A | Benzosulfonic acids as end groups of engineering thermoplastic resins; fireproofing; oxidation and UV resistances; photostabilizers | ATOCHEM NORTH AMERICA, INC. (US) | 1991-05-07 | — | — | US | disclosed |
| EP-0332761-A2 | Single-functional and mixtures of multifunctional oligomeric performance additive compositions, and their use | ELF ATOCHEM NORTH AMERICA, INC. (US) | 1989-09-20 | — | — | EP | disclosed |