SCHEMBL9535859

SCHEMBL9535859

O=C(Cl)c1c(Br)c(Br)c(Br)c(Br)c1C(=O)Cl

nearest known ligand 0.38

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.38
PTPN1 P18031 1/20 0.35
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
CA4 P22748 1/20 0.32
CA6 P23280 1/20 0.32
HPGD P15428 1/20 0.32
ALOX15 P16050 1/20 0.32
MAPK1 P28482 1/20 0.32
RECQL P46063 1/20 0.32
HIF1A Q16665 1/20 0.32
HSD17B10 Q99714 1/20 0.32
GSK3B P49841 1/20 0.31
F2 P00734 1/20 0.30
PRSS1 P07477 1/20 0.30
PRSS2 P07478 1/20 0.30
PRSS3 P35030 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10332292 0.93 ALDH1A1 (0.38) ALDH1A1PTPN1CA1CA2CA4
SCHEMBL11786595 0.90 ALDH1A1 (0.36) ALDH1A1PTPN1CA1CA2CA4
SCHEMBL4658253 0.90 ALDH1A1 (0.39) ALDH1A1PTPN1GSK3B
SCHEMBL11052757 0.83 ALDH1A1 (0.39) ALDH1A1PTPN1GSK3B
SCHEMBL9717140 0.76 MAPT (0.44) ALDH1A1CA1CA2HPGDALOX15
SCHEMBL8913308 0.73 ALDH1A1 (0.47) ALDH1A1ALOX15
SCHEMBL11816572 0.73 CA1 (0.37) ALDH1A1PTPN1CA1CA2CA4
SCHEMBL10615599 0.73 ALDH1A1 (0.40) ALDH1A1PTPN1CA1CA2CA4
SCHEMBL11701959 0.72 PTPN1 (0.40) PTPN1
SCHEMBL11819466 0.71 CA2 (0.40) ALDH1A1CA1CA2CA4CA6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250297056-A1 METHOD FOR PRODUCING POLYETHERKETONEKETONE ARKEMA FRANCE (FR) 2025-09-25 US claimed
EP-4519341-A1 METHOD FOR PRODUCING POLYETHERKETONEKETONE ARKEMA FRANCE (FR) 2025-03-12 EP claimed
CN-119487101-A Method for producing polyetherketoneketone 阿科玛法国公司 2025-02-18 CN claimed
WO-2023214052-A1 METHOD FOR PRODUCING POLYETHERKETONEKETONE ARKEMA FRANCE (FR) 2023-11-09 WO claimed
EP-0178184-B1 PREPARATION OF AROMATIC CARBONYL COMPOUNDS RAYCHEM CORPORATION (a Delaware corporation) (US) 1993-04-28 EP claimed
US-5068447-A Friedel-crafts preparation of aromatic ketones with an inoganic salt controlling agent RAYCHEM CORPORATION (US) 1991-11-26 US claimed
US-4814508-A Friedel-crafts preparation of aromatic ketones RAYCHEM CORPORATION (US) 1989-03-21 US claimed
EP-0178184-A1 Preparation of aromatic carbonyl compounds RAYCHEM CORPORATION (a Delaware corporation) (US) 1986-04-16 EP claimed
US-20250297056-A1 METHOD FOR PRODUCING POLYETHERKETONEKETONE ARKEMA FRANCE (FR) 2025-09-25 US disclosed
EP-4519341-A1 METHOD FOR PRODUCING POLYETHERKETONEKETONE ARKEMA FRANCE (FR) 2025-03-12 EP disclosed
CN-119487101-A Method for producing polyetherketoneketone 阿科玛法国公司 2025-02-18 CN disclosed
CN-113227034-B Method for producing 1, 4-bis (4-phenoxybenzoyl) benzene using substantially unhydrolyzed terephthaloyl chloride 阿科玛法国公司 2024-07-02 CN disclosed
EP-3650433-B1 METHOD FOR MANUFACTURING 1,4-BIS (4-PHENOXYBENZOYLBENZENE) AT AN ELEVATED TEMPERATURE ARKEMA FRANCE (FR) 2024-04-24 EP disclosed
CN-113272270-B Method for producing 1, 4-bis (4-phenoxybenzoyl) benzene at elevated temperature 阿科玛法国公司 2024-04-16 CN disclosed
US-20190077739-A1 DISSOCIATION OF 1,4-BIS (4-PHENOXYBENZOYL)BENZENE - LEWIS ACID COMPLEX IN A PROTIC SOLVENT ARKEMA FRANCE (FR) 2019-03-14 US disclosed
EP-0178184-B1 PREPARATION OF AROMATIC CARBONYL COMPOUNDS RAYCHEM CORPORATION (a Delaware corporation) (US) 1993-04-28 EP disclosed
US-5068447-A Friedel-crafts preparation of aromatic ketones with an inoganic salt controlling agent RAYCHEM CORPORATION (US) 1991-11-26 US disclosed
US-4814508-A Friedel-crafts preparation of aromatic ketones RAYCHEM CORPORATION (US) 1989-03-21 US disclosed
EP-0178184-A1 Preparation of aromatic carbonyl compounds RAYCHEM CORPORATION (a Delaware corporation) (US) 1986-04-16 EP disclosed
US-4567242-A NO FREE HYDROXYL END GROUPS DAI-ICHI KOGYO SEIYAKU CO., LTD. (JP) 1986-01-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190077739-A1 DISSOCIATION OF 1,4-BIS (4-PHENOXYBENZOYL)BENZENE - LEWIS ACID COMPLEX IN A PROTIC SOLVENT PBRM1, PSMB7, PSMC2 ALDH1A1 2574/4885PTPN1 2474/4885CA1 239/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.