Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | MIF | P14174 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.37 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.37 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.37 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.37 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.37 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15070049 | 0.83 | TSHR (0.46) | MEN1KMT2ASMN1; SMN2CYP1A2NPC1 | |
| SCHEMBL10693103 | 0.82 | KMT2A (0.43) | MEN1KMT2AMIFCYP19A1NPSR1 | |
| SCHEMBL6797392 | 0.81 | TSHR (0.46) | MEN1KMT2ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL1774301 | 0.81 | CYP2C19 (0.41) | KMT2ASMN1; SMN2CYP2C19NPC1RAB9A | |
| SCHEMBL6796615 | 0.80 | TYR (0.45) | POLBSMN1; SMN2NPC1RAB9ALMNA | |
| SCHEMBL9714690 | 0.79 | ESR1 (0.54) | MEN1KMT2AHSD17B10SLC6A2SLC6A4 | |
| SCHEMBL5166644 | 0.79 | TP53 (0.39) | MEN1KMT2ASMN1; SMN2LMNATSHR | |
| SCHEMBL28276711 | 0.79 | CA1 (0.34) | MEN1KMT2ANPSR1POLBSMN1; SMN2 | |
| SCHEMBL6280416 | 0.78 | KMT2A (0.52) | MEN1KMT2AMIFCYP19A1NPSR1 | |
| SCHEMBL4558928 | 0.76 | KIF11 (0.42) | L3MBTL1SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0436860-A1 | Process for the preparation of 2-(4-chlorophenyl)-3-methyl-butanoic acid | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-07-17 | — | — | EP | claimed |
| JP-4253935-A | — | — | None | — | — | JP | disclosed |
| JP-H04253935-A | PRODUCTION OF 2-(4-CHLORPHENYL)-3-METHYLBUTYRIC ACID | HOECHST AG | 1992-09-09 | — | — | JP | disclosed |
| US-5072037-A | Aldol condensation, hydrogenation, dehydration, hydroformylati on, oxidation; purity, by-product inhibition, pollution contro l | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-12-10 | — | — | US | disclosed |
| EP-0436860-A1 | Process for the preparation of 2-(4-chlorophenyl)-3-methyl-butanoic acid | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-07-17 | — | — | EP | disclosed |