Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 7/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 9/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 7/20 | 0.42 |
| ▸ | NR3C1 | P04150 | 6/20 | 0.42 |
| ▸ | PGR | P06401 | 5/20 | 0.42 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 4/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | BLM | P54132 | 2/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.41 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | AR | P10275 | 3/20 | 0.40 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9717206 | 1.00 | KDM4E (0.60) | KDM4ELMNASMN1; SMN2HIF1ACYP3A4 | |
| SCHEMBL9521229 | 0.88 | LMNA (0.69) | KDM4ELMNASMN1; SMN2HIF1ACYP3A4 | |
| SCHEMBL20821236 | 0.88 | LMNA (0.55) | KDM4ELMNASMN1; SMN2HIF1ACYP3A4 | |
| SCHEMBL19762243 | 0.88 | LMNA (0.69) | KDM4ELMNASMN1; SMN2HIF1ACYP3A4 | |
| SCHEMBL29043217 | 0.88 | LMNA (0.69) | KDM4ELMNASMN1; SMN2HIF1ACYP3A4 | |
| SCHEMBL9521233 | 0.88 | LMNA (0.69) | KDM4ELMNASMN1; SMN2HIF1ACYP3A4 | |
| SCHEMBL21091789 | 0.87 | LMNA (0.54) | KDM4ELMNASMN1; SMN2HIF1ACYP3A4 | |
| SCHEMBL9717259 | 0.84 | KDM4E (0.51) | KDM4ELMNASMN1; SMN2HIF1ACYP3A4 | |
| SCHEMBL9739294 | 0.82 | ALDH1A1 (0.60) | KDM4ELMNASMN1; SMN2HIF1ACYP3A4 | |
| SCHEMBL9739289 | 0.82 | ALDH1A1 (0.60) | KDM4ELMNASMN1; SMN2HIF1ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0278319-B1 | 9,11-EPOXY-21-HYDROXYPREGNANE DERIVATIVES | THE UPJOHN COMPANY (US) | 1992-10-07 | — | — | EP | claimed |
| EP-0308412-B1 | 16$g(a)-METHYLATION PROCESS | THE UPJOHN COMPANY (US) | 1992-03-18 | — | — | EP | claimed |