Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | RARB | P10826 | 8/20 | 0.37 |
| ▸ | RARA | P10276 | 2/20 | 0.36 |
| ▸ | RARG | P13631 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9717244 | 0.95 | TAAR1 (0.42) | NPC1NFKB1MAPK1RAB9ANFKB2 | |
| SCHEMBL2130427 | 0.78 | RAB9A (0.49) | NPC1NFKB1MAPK1RAB9ANFKB2 | |
| SCHEMBL2050263 | 0.77 | NPC1 (0.64) | NPC1NFKB1MAPK1RAB9ANFKB2 | |
| SCHEMBL10048204 | 0.76 | IDO1 (0.55) | L3MBTL1SIGMAR1MEN1KMT2A | |
| SCHEMBL1599747 | 0.76 | RARB (0.58) | NPC1NFKB1MAPK1RAB9ANFKB2 | |
| SCHEMBL22989786 | 0.74 | HSD17B10 (0.61) | NPC1NFKB1MAPK1RAB9ANFKB2 | |
| SCHEMBL31270913 | 0.74 | HSD17B10 (0.61) | NPC1NFKB1MAPK1RAB9ANFKB2 | |
| SCHEMBL10455067 | 0.74 | HSD17B10 (0.61) | NPC1NFKB1MAPK1RAB9ANFKB2 | |
| SCHEMBL8607022 | 0.74 | HSD17B10 (0.61) | NPC1NFKB1MAPK1RAB9ANFKB2 | |
| SCHEMBL4908685 | 0.74 | HSD17B10 (0.61) | NPC1NFKB1MAPK1RAB9ANFKB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5137653-A | Alkanoyl ester compounds and their intermediates and method of producing the same | NIPPON MINING CO., LTD. (JP) | 1992-08-11 | — | — | US | disclosed |
| EP-0311692-B1 | NOVEL ALKANOYL ESTER COMPOUNDS, INTERMEDIATES THEREFOR, AND PROCESSES FOR THEIR PREPARATION | NIPPON MINING COMPANY LIMITED (JP) | 1992-07-08 | — | — | EP | disclosed |
| EP-0311692-A1 | NOVEL ALKANOYL ESTER COMPOUNDS, INTERMEDIATES THEREFOR, AND PROCESSES FOR THEIR PREPARATION | NIPPON MINING COMPANY LIMITED (JP) | 1989-04-19 | — | — | EP | disclosed |