Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.64 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.64 |
| ▸ | RAB9A | P51151 | 1/20 | 0.64 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.64 |
| ▸ | RELA | Q04206 | 1/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.64 |
| ▸ | RARB | P10826 | 6/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | RARA | P10276 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | MTOR | P42345 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1599747 | 0.94 | RARB (0.58) | NPC1NFKB1MAPK1RAB9ANFKB2 | |
| SCHEMBL27881438 | 0.93 | SMN1; SMN2 (0.59) | NPC1NFKB1MAPK1RAB9ANFKB2 | |
| SCHEMBL687846 | 0.93 | SMN1; SMN2 (0.59) | NPC1NFKB1MAPK1RAB9ANFKB2 | |
| SCHEMBL22989786 | 0.92 | HSD17B10 (0.61) | NPC1NFKB1MAPK1RAB9ANFKB2 | |
| SCHEMBL4908685 | 0.92 | HSD17B10 (0.61) | NPC1NFKB1MAPK1RAB9ANFKB2 | |
| SCHEMBL26226733 | 0.92 | HSD17B10 (0.61) | NPC1NFKB1MAPK1RAB9ANFKB2 | |
| SCHEMBL10528231 | 0.92 | HSD17B10 (0.61) | NPC1NFKB1MAPK1RAB9ANFKB2 | |
| SCHEMBL10455067 | 0.92 | HSD17B10 (0.61) | NPC1NFKB1MAPK1RAB9ANFKB2 | |
| SCHEMBL8607022 | 0.92 | HSD17B10 (0.61) | NPC1NFKB1MAPK1RAB9ANFKB2 | |
| SCHEMBL31270913 | 0.92 | HSD17B10 (0.61) | NPC1NFKB1MAPK1RAB9ANFKB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12297386-B2 | Aromatic isothiocyanates | MERCK PATENT GMBH (DE) | 2025-05-13 | — | — | US | disclosed |
| EP-4237507-B1 | AROMATIC ISOTHIOCYANATES | MERCK PATENT GMBH (DE) | 2025-04-30 | — | — | EP | disclosed |
| CN-116601265-B | Aromatic isothiocyanates | 默克专利股份有限公司 | 2025-02-25 | — | — | CN | disclosed |
| CN-114829543-B | Aromatic isothiocyanates | 默克专利股份有限公司 | 2024-09-10 | — | — | CN | disclosed |
| CN-115745833-B | Preparation method of 4-alkyl-4' -cyanobiphenyl | 宁夏中星显示材料有限公司 | 2024-07-05 | — | — | CN | disclosed |
| EP-4073205-B1 | AROMATIC ISOTHIOCYANATES | MERCK PATENT GMBH (DE) | 2024-06-12 | — | — | EP | disclosed |
| US-20240117249-A1 | AROMATIC ISOTHIOCYANATES | MERCK PATENT GMBH (DE) | 2024-04-11 | — | — | US | disclosed |
| CN-117210227-A | Room temperature stable crystallization-free twisted bending nematic liquid crystal dimer material and application thereof | 华东理工大学 | 2023-12-12 | — | — | CN | disclosed |
| US-11834599-B2 | Aromatic isothiocyanates | MERCK PATENT GMBH (DE) | 2023-12-05 | — | — | US | disclosed |
| US-11834599-B2 | Aromatic isothiocyanates | MERCK PATENT GMBH (DE) | 2023-12-05 | — | — | US | disclosed |
| US-20110210322-A1 | POLYMER COMPOUND CONTAINING NITROGEN-CONTAINING HETEROCYCLIC STRUCTURE, AND COMPOSITION, SOLUTION, THIN FILM AND POLYMER LIGHT-EMITTING ELEMENT EACH CONTAINING SAME | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-09-01 | — | — | US | disclosed |
| EP-2336215-A1 | POLYMER COMPOUND CONTAINING NITROGEN-CONTAINING HETEROCYCLIC STRUCTURE, AND COMPOSITION, SOLUTION, THIN FILM AND POLYMER LIGHT-EMITTING ELEMENT EACH CONTAINING SAME | Sumitomo Chemical Company, Limited (JP) | 2011-06-22 | — | — | EP | disclosed |
| US-7820251-B2 | Liquid crystal compound and liquid crystal display utilizing the same | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) | 2010-10-26 | — | — | US | disclosed |
| US-20100230666-A1 | AMINE-TYPE POLYMERIC COMPOUND, AND LIGHT-EMITTING ELEMENT COMPRISING THE SAME | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-09-16 | — | — | US | disclosed |
| EP-2216356-A1 | AMINE-TYPE POLYMERIC COMPOUND, AND LIGHT-EMITTING ELEMENT COMPRISING THE SAME | Sumitomo Chemical Company, Limited (JP) | 2010-08-11 | — | — | EP | disclosed |
| US-7648743-B2 | Liquid crystal compound and liquid crystal display utilizing the same | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) | 2010-01-19 | — | — | US | disclosed |
| US-20100009099-A1 | LIQUID CRYSTAL COMPOUND AND LIQUID CRYSTAL DISPLAY UTILIZING THE SAME | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) | 2010-01-14 | — | — | US | disclosed |
| US-20090123666-A1 | LIQUID CRYSTAL COMPOUND AND LIQUID CRYSTAL DISPLAY UTILIZING THE SAME | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) | 2009-05-14 | — | — | US | disclosed |
| US-7479575-B2 | Method for preparing para-phenyl alkynyl benzaldehydes | LABORATOIRES SERONO SA (CH) | 2009-01-20 | — | — | US | disclosed |
| US-20080108849-A1 | Method For Preparing Para-Phenyl Alkynyl Benzaldehydes | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2008-05-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080108849-A1 | Method For Preparing Para-Phenyl Alkynyl Benzaldehydes | TNNC1, CPT1B, MUSK | NPC1 3688/4885NFKB1 1878/4885MAPK1 1361/4885 |
| US-20090123666-A1 | LIQUID CRYSTAL COMPOUND AND LIQUID CRYSTAL DISPLAY UTILIZING THE SAME | FZD7, PYCARD, DVL1 | NPC1 2791/4885NFKB1 4380/4885MAPK1 2682/4885 |
| US-20100230666-A1 | AMINE-TYPE POLYMERIC COMPOUND, AND LIGHT-EMITTING ELEMENT COMPRISING THE SAME | AHR, ARNT, MLLT1 | NPC1 4200/4885NFKB1 3092/4885MAPK1 907/4885 |
| US-20240117249-A1 | AROMATIC ISOTHIOCYANATES | TRPA1, FOXM1, MAFG | NPC1 1048/4885NFKB1 1044/4885MAPK1 248/4885 |
| US-12297386-B2 | Aromatic isothiocyanates | TRPA1, FOXM1, MAFG | NPC1 1048/4885NFKB1 1044/4885MAPK1 248/4885 |
| US-20100009099-A1 | LIQUID CRYSTAL COMPOUND AND LIQUID CRYSTAL DISPLAY UTILIZING THE SAME | FZD7, PYCARD, DVL1 | NPC1 2791/4885NFKB1 4380/4885MAPK1 2682/4885 |
| US-20110210322-A1 | POLYMER COMPOUND CONTAINING NITROGEN-CONTAINING HETEROCYCLIC STRUCTURE, AND COMPOSITION, SOLUTION, THIN FILM AND POLYMER LIGHT-EMITTING ELEMENT EACH CONTAINING SAME | H1-10, RNF10, F10 | NPC1 2235/4885NFKB1 1333/4885MAPK1 1856/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.