Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.40 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.40 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.40 |
| ▸ | NAAA | Q02083 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.39 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5423814 | 0.98 | SIGMAR1 (0.44) | SIGMAR1NR1I2HTR2AAOC3OPRM1 | |
| SCHEMBL4181323 | 0.96 | NR1I2 (0.46) | SIGMAR1NR1I2HTR2AAOC3OPRM1 | |
| SCHEMBL3072581 | 0.96 | NR1I2 (0.46) | SIGMAR1NR1I2HTR2AAOC3OPRM1 | |
| SCHEMBL7614200 | 0.96 | NR1I2 (0.46) | SIGMAR1NR1I2HTR2AAOC3OPRM1 | |
| SCHEMBL8509029 | 0.96 | NR1I2 (0.46) | SIGMAR1NR1I2HTR2AAOC3OPRM1 | |
| SCHEMBL1331317 | 0.96 | NR1I2 (0.46) | SIGMAR1NR1I2HTR2AAOC3OPRM1 | |
| SCHEMBL31175819 | 0.96 | NR1I2 (0.46) | SIGMAR1NR1I2HTR2AAOC3OPRM1 | |
| SCHEMBL4873076 | 0.96 | NR1I2 (0.46) | SIGMAR1NR1I2HTR2AAOC3OPRM1 | |
| SCHEMBL21633720 | 0.96 | NR1I2 (0.46) | SIGMAR1NR1I2HTR2AAOC3OPRM1 | |
| SCHEMBL7169115 | 0.94 | SIGMAR1 (0.47) | SIGMAR1NR1I2HTR2AOPRM1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5137653-A | Alkanoyl ester compounds and their intermediates and method of producing the same | NIPPON MINING CO., LTD. (JP) | 1992-08-11 | — | — | US | disclosed |
| EP-0311692-B1 | NOVEL ALKANOYL ESTER COMPOUNDS, INTERMEDIATES THEREFOR, AND PROCESSES FOR THEIR PREPARATION | NIPPON MINING COMPANY LIMITED (JP) | 1992-07-08 | — | — | EP | disclosed |
| EP-0311692-A1 | NOVEL ALKANOYL ESTER COMPOUNDS, INTERMEDIATES THEREFOR, AND PROCESSES FOR THEIR PREPARATION | NIPPON MINING COMPANY LIMITED (JP) | 1989-04-19 | — | — | EP | disclosed |