SCHEMBL9717359

SCHEMBL9717359

CCCCCCCCCCCCONC(C)C

nearest known ligand 0.39

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
DNM1 Q05193 1/20 0.39
THRB P10828 2/20 0.38
TSHR P16473 1/20 0.38
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
FAAH O00519 1/20 0.38
MAPK1 P28482 1/20 0.38
EPHX1 P07099 1/20 0.38
HTT P42858 1/20 0.37
MAPT P10636 1/20 0.37
USP2 O75604 1/20 0.36
SPHK1 Q9NYA1 1/20 0.36
LPAR3 Q9UBY5 5/20 0.35
LPAR2 Q9HBW0 4/20 0.35
CA1 P00915 4/20 0.35
CA2 P00918 4/20 0.35
CA9 Q16790 4/20 0.35
LPAR1 Q92633 2/20 0.35
NAAA Q02083 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7859946 0.98 DNM1 (0.35) DNM1THRBTSHRMEN1KMT2A
SCHEMBL16409823 0.90
SCHEMBL10951270 0.77 DNM1 (0.36) DNM1THRBTSHRMEN1KMT2A
SCHEMBL29245611 0.77 CA1 (0.34) DNM1THRBTSHRMEN1KMT2A
SCHEMBL28574966 0.76 ZDHHC7 (0.36) DNM1THRBTSHRMEN1KMT2A
SCHEMBL29082218 0.76 ZDHHC7 (0.36) DNM1THRBTSHRMEN1KMT2A
SCHEMBL4280445 0.74 DNM1 (0.42) DNM1THRBTSHRMEN1KMT2A
SCHEMBL298989 0.74 EPHX1 (0.33) TSHRMAPK1EPHX1LPAR3LPAR2
SCHEMBL298990 0.74 EPHX1 (0.33) TSHRMAPK1EPHX1LPAR3LPAR2
SCHEMBL4271919 0.74 DNM1 (0.42) DNM1THRBTSHRMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118271422-A Transfection complexes and methods of use thereof 分子传递有限公司 2024-07-02 CN disclosed
WO-2017139697-A9 BACTERIA ENGINEERED TO TREAT DISEASES ASSOCIATED WITH HYPERAMMONEMIA SYNLOGIC, INC. (US) 2017-12-07 WO disclosed
US-5122541-A Alcohol anionic surfactant, alkalizing or acidifying agent STERLING DRUG, INC. (US) 1992-06-16 US disclosed