SCHEMBL7859946

SCHEMBL7859946

CCCCCONC(C)C

nearest known ligand 0.35

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
DNM1 Q05193 1/20 0.35
MEN1 O00255 2/20 0.34
KMT2A Q03164 2/20 0.34
EPHX1 P07099 2/20 0.34
FAAH O00519 1/20 0.34
MAPK1 P28482 1/20 0.34
THRB P10828 2/20 0.33
CA1 P00915 2/20 0.33
CA2 P00918 2/20 0.33
CA9 Q16790 2/20 0.33
HTT P42858 2/20 0.33
SPHK1 Q9NYA1 1/20 0.33
OPRM1 P35372 1/20 0.33
TSHR P16473 1/20 0.33
USP2 O75604 1/20 0.33
CA12 O43570 1/20 0.33
MAPT P10636 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9717359 0.98 DNM1 (0.39) DNM1MEN1KMT2AEPHX1FAAH
SCHEMBL16409823 0.92
SCHEMBL298989 0.76 EPHX1 (0.33) EPHX1MAPK1CA1CA2CA9
SCHEMBL298990 0.76 EPHX1 (0.33) EPHX1MAPK1CA1CA2CA9
SCHEMBL10951270 0.75 DNM1 (0.36) DNM1MEN1KMT2AEPHX1FAAH
SCHEMBL9799487 0.75 USP2 (0.38) MEN1KMT2AEPHX1THRBCA1
SCHEMBL29245611 0.74 CA1 (0.34) DNM1MEN1KMT2AEPHX1MAPK1
SCHEMBL5682470 0.73
SCHEMBL811627 0.73 ADRB2 (0.35) FAAHTHRBTSHR
SCHEMBL29082218 0.73 ZDHHC7 (0.36) DNM1MEN1KMT2AEPHX1FAAH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10465019-B2 Catalysts for preparation of ultra high molecular weight polyethylene (UHMWPE) and process for preparation thereof COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2019-11-05 US disclosed
US-20180171039-A1 CATALYSTS FOR PREPARATION OF ULTRA HIGH MOLECULAR WEIGHT POLYETHYLENE (UHMWPE) AND PROCESS FOR PREPARATION THEREOF COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2018-06-21 US disclosed
EP-1086063-A4 NOVEL POTASSIUM CHANNEL DRUGS AND THEIR USES ADVANCED MEDICINE INC (US) 2001-03-28 EP disclosed
EP-1086063-A1 NOVEL POTASSIUM CHANNEL DRUGS AND THEIR USES Advanced Medicine, Inc. (US) 2001-03-28 EP disclosed
WO-1999064050-A9 NOVEL POTASSIUM CHANNEL DRUGS AND THEIR USES ADVANCED MEDICINE INC (US) 2000-04-20 WO disclosed
WO-1999064050-A1 NOVEL POTASSIUM CHANNEL DRUGS AND THEIR USES ADVANCED MEDICINE, INC. (US) 1999-12-16 WO disclosed