SCHEMBL9717427

SCHEMBL9717427

C=C(c1ccc(C)cc1)c1ccc(C(C)C=O)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.38
HTT P42858 4/20 0.38
LMNA P02545 4/20 0.38
NPSR1 Q6W5P4 3/20 0.38
SMN1; SMN2 Q16637 3/20 0.38
PKM P14618 2/20 0.38
ATM Q13315 2/20 0.38
HPGD P15428 2/20 0.38
TDP1 Q9NUW8 2/20 0.38
NLRP1 Q9C000 1/20 0.38
MEN1 O00255 1/20 0.38
NTSR1 P30989 1/20 0.38
KMT2A Q03164 1/20 0.38
CES2 O00748 2/20 0.38
CES1 P23141 2/20 0.38
STAT3 P40763 1/20 0.36
ACHE P22303 1/20 0.35
ALOX5 P09917 1/20 0.35
MAPT P10636 3/20 0.34
GFER P55789 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9717396 0.86 MEN1 (0.46) ALDH1A1HTTLMNANPSR1SMN1; SMN2
SCHEMBL1532439 0.84 CYP2A6 (0.44) ALDH1A1HTTLMNANPSR1SMN1; SMN2
SCHEMBL872965 0.84 CYP2A6 (0.44) ALDH1A1HTTLMNANPSR1SMN1; SMN2
SCHEMBL4831627 0.84 CYP2A6 (0.44) ALDH1A1HTTLMNANPSR1SMN1; SMN2
Isobutane SCHEMBL19460561 0.82 CYP2A6 (0.42) ALDH1A1HTTLMNANPSR1SMN1; SMN2
SCHEMBL6546351 0.79 HTT (0.47) ALDH1A1HTTLMNASMN1; SMN2MEN1
SCHEMBL4412916 0.76 HTT (0.55) ALDH1A1HTTLMNANPSR1SMN1; SMN2
SCHEMBL893597 0.76 HTT (0.55) ALDH1A1HTTLMNANPSR1SMN1; SMN2
SCHEMBL21628043 0.76 TYR (0.46)
SCHEMBL9715740 0.75 PTGS2 (0.50) ALDH1A1LMNASMN1; SMN2HPGDCES2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0311689-B1 PROCESS FOR SELECTIVELY MONOHYDROFORMYLATING DIOLEFIN NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1992-06-10 EP disclosed
US-4982007-A CARBONYLATION CATALYST NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1991-01-01 US disclosed
EP-0311689-A1 PROCESS FOR SELECTIVELY MONOHYDROFORMYLATING DIOLEFIN NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1989-04-19 EP disclosed