Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 2/20 | 0.62 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | SHBG | P04278 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | GMNN | O75496 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | BLM | P54132 | 1/20 | 0.54 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21725621 | 0.85 | EPHX1 (0.52) | EPHX1TP53SHBGKDM4EGMNN | |
| SCHEMBL23436213 | 0.85 | EPHX1 (0.52) | EPHX1TP53SHBGKDM4EGMNN | |
| SCHEMBL20663914 | 0.81 | EPHX1 (0.48) | EPHX1TP53SHBGKDM4EGMNN | |
| SCHEMBL629725 | 0.81 | EPHX1 (0.48) | EPHX1TP53SHBGKDM4EGMNN | |
| SCHEMBL22400211 | 0.79 | SHBG (0.58) | EPHX1TP53SHBGKDM4EGMNN | |
| SCHEMBL904038 | 0.78 | EPHX1 (0.56) | EPHX1TP53SHBGKDM4EGMNN | |
| SCHEMBL4379254 | 0.77 | EPHX1 (0.62) | EPHX1TP53SHBGKDM4EGMNN | |
| SCHEMBL635367 | 0.77 | EPHX1 (1.00) | EPHX1TP53SHBGKDM4EGMNN | |
| SCHEMBL21656667 | 0.74 | EPHX1 (0.59) | EPHX1TP53SHBGKDM4EGMNN | |
| SCHEMBL23082587 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0338386-B1 | NEW METHOD OF PREPARATION OF OXALIC ACID ESTERS AND AMIDES | Enichem Anic S.r.l. (IT) | 1992-09-02 | — | — | EP | disclosed |
| US-4981963-A | Method of preparation of oxalic acid esters and amides | ENICHEM ANIC S.P.A. (IT) | 1991-01-01 | — | — | US | disclosed |
| EP-0338386-A1 | New method of preparation of oxalic acid esters and amides | Enichem Anic S.r.l. (IT) | 1989-10-25 | — | — | EP | disclosed |