Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 3/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | GMNN | O75496 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | SHBG | P04278 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23082587 | 0.97 | — | — | |
| SCHEMBL21912822 | 0.86 | — | — | |
| SCHEMBL9717438 | 0.78 | EPHX1 (0.62) | EPHX1TP53KDM4EGMNNLMNA | |
| SCHEMBL11834390 | 0.76 | EPHX1 (0.40) | EPHX1TP53KDM4EGMNNLMNA | |
| SCHEMBL13619070 | 0.74 | SHBG (0.56) | EPHX1TP53KDM4EGMNNLMNA | |
| SCHEMBL6447100 | 0.74 | EPHX1 (0.39) | EPHX1TP53KDM4EGMNNLMNA | |
| SCHEMBL635367 | 0.72 | EPHX1 (1.00) | EPHX1TP53KDM4EGMNNLMNA | |
| SCHEMBL4379254 | 0.72 | EPHX1 (0.62) | EPHX1TP53KDM4EGMNNLMNA | |
| SCHEMBL11698385 | 0.70 | — | — | |
| SCHEMBL21656667 | 0.70 | EPHX1 (0.59) | EPHX1TP53KDM4EGMNNLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012041253-A1 | COMPOUNDS FOR INCREASE OF HDL-C LEVEL AND USES THEREOF | ZHEJIANG BETA PHARMA INC. (CN) | 2012-04-05 | — | — | WO | disclosed |