Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.77 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.77 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.77 |
| ▸ | ATM | Q13315 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | NAMPT | P43490 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.49 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.49 |
| ▸ | ACR | P10323 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.47 |
| ▸ | MMP13 | P45452 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5856532 | 0.90 | ATM (0.73) | GAAKMT2AHSD17B10ATMSMN1; SMN2 | |
| SCHEMBL16879593 | 0.89 | HSD17B10 (0.61) | GAAKMT2AHSD17B10ATMSMN1; SMN2 | |
| SCHEMBL2290271 | 0.89 | GAA (0.61) | GAAKMT2AHSD17B10ATMSMN1; SMN2 | |
| SCHEMBL3377096 | 0.87 | NPC1 (0.66) | GAAKMT2AHSD17B10SMN1; SMN2NAMPT | |
| SCHEMBL8506869 | 0.87 | NPC1 (0.66) | GAAKMT2AHSD17B10SMN1; SMN2NAMPT | |
| SCHEMBL8507006 | 0.87 | NPC1 (0.66) | GAAKMT2AHSD17B10SMN1; SMN2NAMPT | |
| SCHEMBL30098920 | 0.86 | MMP13 (0.59) | GAAKMT2AHSD17B10SMN1; SMN2NPC1 | |
| SCHEMBL30098939 | 0.86 | MMP13 (0.59) | GAAKMT2AHSD17B10SMN1; SMN2NPC1 | |
| SCHEMBL6889431 | 0.81 | GAA (0.87) | GAAKMT2AHSD17B10ATMSMN1; SMN2 | |
| SCHEMBL27727377 | 0.81 | GAA (0.87) | GAAKMT2AHSD17B10ATMSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5086104-A | Mixture of thermoplastic resin, elastomer and amide compound, excellent toughtness, heat resistance and durability | POLYPLASTICS CO., LTD. (JP) | 1992-02-04 | — | — | US | disclosed |