Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.53 |
| ▸ | F3 | P13726 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | CES2 | O00748 | 1/20 | 0.52 |
| ▸ | CES1 | P23141 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 4/20 | 0.50 |
| ▸ | CA2 | P00918 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | PARP1 | P09874 | 1/20 | 0.48 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.48 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.48 |
| ▸ | PARP4 | Q9UKK3 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | XDH | P47989 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4904356 | 0.87 | MAPT (0.59) | MAPTF3HPGDRAB9ACES2 | |
| SCHEMBL273504 | 0.87 | ALDH1A1 (0.52) | MAPTHPGDRAB9AALDH1A1KMT2A | |
| P-Methoxy-Acetophenone SCHEMBL27987328 | 0.85 | MAPT (0.56) | MAPTHPGDRAB9ACES2CES1 | |
| SCHEMBL12243319 | 0.85 | F3 (0.66) | MAPTF3RAB9AALDH1A1KDM4E | |
| SCHEMBL14336693 | 0.85 | F3 (0.66) | MAPTF3RAB9AALDH1A1KDM4E | |
| P-Methoxy-Acetophenone SCHEMBL27987355 | 0.85 | MAPT (0.64) | MAPTHPGDRAB9ACES2CES1 | |
| P-Methoxy-Acetophenone SCHEMBL41285 | 0.84 | MAPT (0.70) | MAPTHPGDRAB9ACES2CES1 | |
| SCHEMBL28924617 | 0.83 | MAPT (0.68) | MAPTF3HPGDCES2CES1 | |
| SCHEMBL3132842 | 0.83 | MAPT (0.68) | MAPTF3HPGDCES2CES1 | |
| SCHEMBL13607266 | 0.83 | MAPT (0.68) | MAPTF3HPGDCES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5162285-A | Carbonylation of Rhodium Salts, Reaction with Ozone or Oxygen | PRINCETON UNIVERSITY (US) | 1992-11-10 | — | — | US | disclosed |
| US-5126490-A | Rhodium carbonyl catalyst | PRINCETON UNIVERSITY (US) | 1992-06-30 | — | — | US | disclosed |