Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | GSK3B | P49841 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 4/20 | 0.49 |
| ▸ | RAB9A | P51151 | 4/20 | 0.49 |
| ▸ | MAOA | P21397 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.44 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.44 |
| ▸ | PAM | P19021 | 1/20 | 0.44 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.44 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.44 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30621821 | 0.91 | CYP1B1 (0.58) | MAPTGSK3BMAOBRAB9AMAOA | |
| SCHEMBL8726134 | 0.83 | F3 (0.53) | MAPTMAOBRAB9AMAOAPOLB | |
| SCHEMBL27334160 | 0.82 | MAPT (0.50) | MAPTMAOBRAB9AMAOAPOLB | |
| SCHEMBL9044093 | 0.81 | PAM (0.68) | MAPTMAOBRAB9AMAOAPOLB | |
| SCHEMBL2608077 | 0.81 | FOS (0.50) | MAPTMAOBRAB9AMAOAPOLB | |
| SCHEMBL9044098 | 0.81 | PAM (0.68) | MAPTMAOBRAB9AMAOAPOLB | |
| SCHEMBL9717482 | 0.81 | F3 (0.58) | MAPTGSK3BMAOBRAB9AMAOA | |
| SCHEMBL7816689 | 0.79 | GRIK1 (0.49) | MAPTMAOBRAB9AMAOAPOLB | |
| SCHEMBL28601348 | 0.79 | MAPT (0.56) | MAPTGSK3BMAOBRAB9AMAOA | |
| SCHEMBL1158301 | 0.77 | PAM (0.68) | MAPTGSK3BMAOBRAB9AMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5162285-A | Carbonylation of Rhodium Salts, Reaction with Ozone or Oxygen | PRINCETON UNIVERSITY (US) | 1992-11-10 | — | — | US | disclosed |
| US-5126490-A | Rhodium carbonyl catalyst | PRINCETON UNIVERSITY (US) | 1992-06-30 | — | — | US | disclosed |