Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 5/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | TP53 | P04637 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.41 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.41 |
| ▸ | GSTA1 | P08263 | 1/20 | 0.41 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | MAP2K6 | P52564 | 1/20 | 0.41 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.41 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.41 |
| ▸ | PLIN5 | Q00G26 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13284004 | 0.81 | ALDH1A1 (0.60) | HPGDTSHRALDH1A1TP53LMNA | |
| SCHEMBL9717650 | 0.80 | GSTP1 (0.67) | HPGDTSHRALDH1A1TP53LMNA | |
| SCHEMBL9717544 | 0.75 | GSTP1 (0.69) | HPGDTSHRALDH1A1TP53LMNA | |
| SCHEMBL11201255 | 0.75 | THRB (0.46) | TSHRALDH1A1TP53LMNACYP2C9 | |
| SCHEMBL11660551 | 0.73 | ALDH1A1 (0.46) | TSHRALDH1A1TP53LMNACYP2C9 | |
| SCHEMBL9717493 | 0.72 | HPGD (0.42) | HPGDTSHRALDH1A1TP53LMNA | |
| SCHEMBL9717599 | 0.72 | HPGD (0.42) | HPGDTSHRALDH1A1TP53LMNA | |
| SCHEMBL9717489 | 0.72 | HPGD (0.42) | HPGDTSHRALDH1A1TP53LMNA | |
| SCHEMBL10661025 | 0.71 | HPGD (0.41) | HPGDTSHRALDH1A1TP53LMNA | |
| SCHEMBL10661013 | 0.71 | HPGD (0.41) | HPGDTSHRALDH1A1TP53LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0240256-B1 | COMPOUNDS USEFUL IN TREATING SICKLE CELL ANEMIA | MERCK & CO. INC. (US) | 1992-04-29 | — | — | EP | disclosed |