Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | IDO1 | P14902 | 2/20 | 0.31 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | MITF | O75030 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28670995 | 1.00 | ROCK2 (0.40) | ROCK2CYP3A4TDP1CYP19A1NPSR1 | |
| SCHEMBL301129 | 0.92 | ROCK2 (0.44) | ROCK2CYP3A4TDP1CYP19A1NPSR1 | |
| SCHEMBL54719 | 0.92 | ROCK2 (0.44) | ROCK2CYP3A4TDP1CYP19A1NPSR1 | |
| SCHEMBL301161 | 0.92 | ROCK2 (0.44) | ROCK2CYP3A4TDP1CYP19A1NPSR1 | |
| SCHEMBL9516193 | 0.90 | ROCK2 (0.43) | ROCK2CYP3A4TDP1CYP19A1NPSR1 | |
| SCHEMBL2271458 | 0.90 | ROCK2 (0.43) | ROCK2CYP3A4TDP1CYP19A1NPSR1 | |
| Bromide SCHEMBL8849424 | 0.90 | ROCK2 (0.43) | ROCK2CYP3A4TDP1CYP19A1NPSR1 | |
| SCHEMBL28530861 | 0.90 | ROCK2 (0.43) | ROCK2CYP3A4TDP1CYP19A1NPSR1 | |
| SCHEMBL30727801 | 0.90 | ROCK2 (0.43) | ROCK2CYP3A4TDP1CYP19A1NPSR1 | |
| SCHEMBL9634618 | 0.90 | ROCK2 (0.43) | ROCK2CYP3A4TDP1CYP19A1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992006059-A1 | PROCESS FOR MAKING OLEFINS | HENKEL RESEARCH CORPORATION (US) | 1992-04-16 | — | — | WO | claimed |
| US-5077447-A | Decarbonylation of mixture of acid and anhydride using Group 8 metal or copper catalyst | HENKEL RESEARCH CORPORATION (US) | 1991-12-31 | — | — | US | claimed |
| WO-1992006059-A1 | PROCESS FOR MAKING OLEFINS | HENKEL RESEARCH CORPORATION (US) | 1992-04-16 | — | — | WO | disclosed |
| US-5077447-A | Decarbonylation of mixture of acid and anhydride using Group 8 metal or copper catalyst | HENKEL RESEARCH CORPORATION (US) | 1991-12-31 | — | — | US | disclosed |