Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.36 |
| ▸ | SLC37A4 | O43826 | 1/20 | 0.35 |
| ▸ | RARB | P10826 | 1/20 | 0.35 |
| ▸ | BID | P55957 | 3/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.35 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.35 |
| ▸ | BAK1 | Q16611 | 2/20 | 0.35 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | EP300 | Q09472 | 1/20 | 0.35 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.35 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.35 |
| ▸ | KAT5 | Q92993 | 1/20 | 0.35 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.35 |
| ▸ | LDHA | P00338 | 1/20 | 0.35 |
| ▸ | LDHB | P07195 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21286973 | 0.79 | NPC1 (0.39) | LMNAFFAR1HPGDKDM4EPKM | |
| SCHEMBL5588244 | 0.79 | LDHA (0.43) | FFAR1HCAR2SLC37A4RARBBID | |
| SCHEMBL14989307 | 0.78 | FFAR1 (0.44) | LMNAFFAR1HCAR2SLC37A4RARB | |
| SCHEMBL11114754 | 0.78 | FFAR1 (0.44) | LMNAFFAR1HCAR2SLC37A4RARB | |
| SCHEMBL10760574 | 0.77 | ALDH1A1 (0.36) | LMNAALDH1A1HCAR3MEN1TSHR | |
| SCHEMBL28473054 | 0.76 | FFAR1 (0.43) | LMNAFFAR1HCAR2SLC37A4RARB | |
| SCHEMBL5590405 | 0.75 | LDHA (0.43) | FFAR1HCAR2SLC37A4BIDMCL1 | |
| SCHEMBL11639212 | 0.74 | LDHA (0.38) | LMNAPPARGLDHALDHBDPP4 | |
| SCHEMBL14989169 | 0.74 | FFAR1 (0.42) | LMNAFFAR1HCAR2SLC37A4RARB | |
| SCHEMBL29601412 | 0.74 | FFAR1 (0.42) | LMNAFFAR1HCAR2SLC37A4RARB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0233376-B1 | RADIOPAQUE THERMOPLASTIC RESIN-SILICONE NETWORK RESIN COMPOSITIONS AND MEDICAL-SURGICAL TUBINGS PREPARED THEREFROM | Becton, Dickinson and Company (US) | 1992-01-22 | — | — | EP | claimed |