Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | NAMPT | P43490 | 2/20 | 0.41 |
| ▸ | CTSK | P43235 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CTSS | P25774 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14931099 | 0.89 | RAB9A (0.47) | RAB9ANAMPTCTSKCYP3A4ALDH1A1 | |
| SCHEMBL757280 | 0.85 | CTSK (0.50) | CTSKALDH1A1CTSSMAPT | |
| SCHEMBL4603000 | 0.84 | RAB9A (0.47) | RAB9ANAMPTCTSKCYP3A4ALDH1A1 | |
| SCHEMBL14923474 | 0.83 | RAB9A (0.46) | RAB9ANAMPTCTSKCYP3A4ALDH1A1 | |
| SCHEMBL9717939 | 0.83 | RAB9A (0.45) | RAB9ANAMPTCTSKCYP3A4ALDH1A1 | |
| SCHEMBL14923471 | 0.82 | RAB9A (0.45) | RAB9ANAMPTCTSKCYP3A4CTSS | |
| SCHEMBL739456 | 0.82 | SUCNR1 (0.49) | RAB9ANAMPTCTSKCYP3A4CTSS | |
| SCHEMBL739452 | 0.82 | SUCNR1 (0.49) | RAB9ANAMPTCTSKCYP3A4CTSS | |
| SCHEMBL3371141 | 0.81 | RAB9A (0.47) | RAB9ANAMPTCTSKCYP3A4ALDH1A1 | |
| SCHEMBL18511285 | 0.81 | KCNA5 (0.48) | RAB9ANAMPTCTSKCYP3A4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992019618-A1 | PLATELET ACTIVATING ANTAGONISTS | ABBOTT LABORATORIES (US) | 1992-11-12 | — | — | WO | disclosed |
| US-5149704-A | Pyridyl- or thiazolidineaminesor ureas | ABBOTT LABORATORIES (US) | 1992-09-22 | — | — | US | disclosed |