SCHEMBL9718090

SCHEMBL9718090

CC(C)C(C)(C)[Si](C)(C)OCCCc1ccccc1CC[C@@H]1[C@H](CO)[C@H]2CC[C@@H]1O2

nearest known ligand 0.33

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TBXA2R P21731 5/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9200380 0.92 TBXA2R (0.38) TBXA2R
SCHEMBL9425238 0.84
SCHEMBL9718118 0.79
SCHEMBL6844318 0.75
SCHEMBL9201450 0.74
SCHEMBL9195004 0.73 TBXA2R (0.38) TBXA2R
SCHEMBL9718279 0.72
SCHEMBL9009573 0.71 TAAR1 (0.37)
SCHEMBL9718198 0.69 TBXA2R (0.45) TBXA2R
SCHEMBL9718203 0.69 TBXA2R (0.45) TBXA2R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5153327-A 7-Oxabicycloheptyl substituted heterocyclic amide or ester prostaglandin analogs useful in the treatment of thrombotic and vasospastic disease E. R. SQUIBB & SONS, INC. (US) 1992-10-06 US disclosed