Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 19/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9718198 | 1.00 | TBXA2R (0.45) | TBXA2R | |
| SCHEMBL9718305 | 0.78 | TBXA2R (0.36) | TBXA2R | |
| SCHEMBL8988219 | 0.75 | TBXA2R (0.47) | TBXA2R | |
| SCHEMBL8870972 | 0.75 | TBXA2R (0.47) | TBXA2R | |
| SCHEMBL8870983 | 0.75 | TBXA2R (0.47) | TBXA2R | |
| SCHEMBL9698532 | 0.69 | TBXA2R (0.54) | TBXA2R | |
| SCHEMBL9718090 | 0.69 | TBXA2R (0.33) | TBXA2R | |
| SCHEMBL5385148 | 0.67 | TBXA2R (0.36) | TBXA2R | |
| SCHEMBL14415439 | 0.67 | TBXA2R (0.36) | TBXA2R | |
| SCHEMBL5385156 | 0.67 | TBXA2R (0.36) | TBXA2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5153327-A | 7-Oxabicycloheptyl substituted heterocyclic amide or ester prostaglandin analogs useful in the treatment of thrombotic and vasospastic disease | E. R. SQUIBB & SONS, INC. (US) | 1992-10-06 | — | — | US | disclosed |