Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | CASP1 | P29466 | 1/20 | 0.49 |
| ▸ | CASP7 | P55210 | 1/20 | 0.49 |
| ▸ | NPEPPS | P55786 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9250009 | 0.83 | ALDH1A1 (0.54) | NPSR1MAPTKDM4EALDH1A1POLB | |
| SCHEMBL9250005 | 0.83 | ALDH1A1 (0.54) | NPSR1MAPTKDM4EALDH1A1POLB | |
| SCHEMBL9717855 | 0.74 | KDM4E (0.67) | MAPTKDM4EALDH1A1CASP1CASP7 | |
| SCHEMBL9854093 | 0.72 | POLB (0.46) | NPSR1MAPTKDM4EALDH1A1GAA | |
| SCHEMBL29496159 | 0.71 | MAPT (0.56) | NPSR1TSHRMAPTKDM4EALDH1A1 | |
| SCHEMBL14880628 | 0.71 | MAPT (0.56) | NPSR1TSHRMAPTKDM4EALDH1A1 | |
| SCHEMBL15805084 | 0.71 | MAPT (0.56) | NPSR1TSHRMAPTKDM4EALDH1A1 | |
| SCHEMBL14113922 | 0.71 | MAPT (0.56) | NPSR1TSHRMAPTKDM4EALDH1A1 | |
| SCHEMBL15799419 | 0.71 | MAPT (0.56) | NPSR1TSHRMAPTKDM4EALDH1A1 | |
| SCHEMBL9853999 | 0.71 | POLB (0.58) | KDM4EALDH1A1GAAPOLBTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992019618-A1 | PLATELET ACTIVATING ANTAGONISTS | ABBOTT LABORATORIES (US) | 1992-11-12 | — | — | WO | disclosed |
| US-5149704-A | Pyridyl- or thiazolidineaminesor ureas | ABBOTT LABORATORIES (US) | 1992-09-22 | — | — | US | disclosed |