Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9250005 | 1.00 | ALDH1A1 (0.54) | ALDH1A1KDM4EBLMALOX15POLB | |
| SCHEMBL9853999 | 0.84 | POLB (0.58) | ALDH1A1KDM4EPOLB | |
| Acetic Acid SCHEMBL9854087 | 0.83 | POLB (0.57) | ALDH1A1KDM4EPOLB | |
| SCHEMBL9718128 | 0.83 | NPSR1 (0.50) | ALDH1A1KDM4EPOLBMAPTNPSR1 | |
| SCHEMBL10425283 | 0.82 | ALDH1A1 (0.52) | ALDH1A1KDM4EMAPT | |
| SCHEMBL9740818 | 0.82 | ALDH1A1 (0.52) | ALDH1A1KDM4EMAPT | |
| SCHEMBL11189829 | 0.79 | KDM4E (0.45) | ALDH1A1KDM4E | |
| SCHEMBL11247271 | 0.79 | KDM4E (0.45) | ALDH1A1KDM4E | |
| SCHEMBL8870492 | 0.78 | KDM4E (0.46) | ALDH1A1KDM4EPOLB | |
| SCHEMBL3826056 | 0.78 | KDM4E (0.46) | ALDH1A1KDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5470851-A | Antihistamine, anticoagulants | SANKYO COMPANY, LIMITED (JP) | 1995-11-28 | — | — | US | disclosed |
| US-4987132-A | PLATELET ACTIVATING FACTOR ANTAGONISTS | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1991-01-22 | — | — | US | disclosed |
| EP-0279681-A2 | Saturated heterocyclic carboxamide derivatives | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1988-08-24 | — | — | EP | disclosed |