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Isoproturon

Isoproturon

SCHEMBL9718315

CC(C)c1ccc(NC(=O)N(C)C)cc1.CON(C)C(=O)Nc1ccc(Cl)cc1

nearest known ligand 0.76

Full drug profile on Sugi Atlas →

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ RAB9A P51151 2/20 0.76
▸ PKM P14618 1/20 0.76
▸ TSHR P16473 1/20 0.65
▸ MEN1 O00255 3/20 0.55
▸ KMT2A Q03164 3/20 0.55
▸ TDP1 Q9NUW8 1/20 0.55
▸ HPGD P15428 1/20 0.50
▸ SMN1; SMN2 Q16637 1/20 0.50
▸ NPY5R Q15761 2/20 0.46
▸ APEX1 P27695 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Monolinuron SCHEMBL9021121 0.92 PKM (0.90) RAB9APKMTSHRMEN1KMT2A
Monolinuron SCHEMBL8337749 0.92 PKM (0.90) RAB9APKMTSHRMEN1KMT2A
Monolinuron SCHEMBL9526623 0.92 PKM (0.90) RAB9APKMTSHRMEN1KMT2A
Monolinuron SCHEMBL1701381 0.87 RAB9A (1.00) RAB9APKMTSHRMEN1KMT2A
Monolinuron SCHEMBL65568 0.87 RAB9A (1.00) RAB9APKMTSHRMEN1KMT2A
Isoproturon SCHEMBL62200 0.84 TSHR (0.67) RAB9ATSHRMEN1KMT2AHPGD
Isoproturon SCHEMBL8518619 0.84 TSHR (0.67) RAB9ATSHRMEN1KMT2AHPGD
Linuron SCHEMBL9419428 0.83 PKM (0.74) RAB9APKMTSHRMEN1KMT2A
Isoproturon SCHEMBL28224193 0.82 TSHR (0.65) RAB9ATSHRMEN1KMT2AHPGD
Monuron SCHEMBL8539289 0.81 TSHR (1.00) RAB9APKMTSHRAPEX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5169425-A Synergistic mixture IDEMITSU KOSAN COMPANY LIMITED (JP) 1992-12-08 — — US disclosed