SCHEMBL9718322

SCHEMBL9718322

COC(Cc1ccc(F)cc1)OC

nearest known ligand 0.50

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 2/20 0.50
IDO1 P14902 3/20 0.43
AGXT P21549 2/20 0.43
LOXL2 Q9Y4K0 1/20 0.42
MAOB P27338 2/20 0.42
MAOA P21397 1/20 0.42
TAAR1 Q96RJ0 3/20 0.40
AOC3 Q16853 2/20 0.40
NOS3 P29474 1/20 0.40
NOS1 P29475 1/20 0.40
NOS2 P35228 1/20 0.40
LMNA P02545 1/20 0.39
SLC6A4 P31645 1/20 0.38
TSHR P16473 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6205902 0.80 TRPA1 (0.50) TRPA1IDO1AGXTLOXL2MAOB
SCHEMBL12862072 0.80 TRPA1 (0.46) TRPA1IDO1AGXTLOXL2MAOB
SCHEMBL6205901 0.80 TRPA1 (0.46) TRPA1IDO1AGXTLOXL2MAOB
SCHEMBL9484637 0.78 AGXT (0.44) IDO1AGXTMAOBTAAR1SLC6A4
SCHEMBL7522498 0.78 LPL (0.44) TAAR1SLC6A4TSHR
SCHEMBL5758636 0.77 TRPA1 (0.47) TRPA1IDO1AGXTLOXL2MAOB
SCHEMBL1070963 0.76 SLC6A4 (0.63) IDO1AGXTTAAR1SLC6A4TSHR
SCHEMBL14240823 0.76 PPARG (0.41) TRPA1TAAR1NOS3NOS1SLC6A4
SCHEMBL12433178 0.76 IDO1 (0.43) IDO1MAOBTAAR1SLC6A4
SCHEMBL9260666 0.76 TAAR1 (0.56) IDO1TAAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5130435-A Elimination of alcohol from an acetal or ketal in the presence of phosphates BASF AKTIENGESELLSCHAFT (DE) 1992-07-14 US disclosed