Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 5/20 | 0.42 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | CDC25B | P30305 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9718201 | 1.00 | ALOX15 (0.42) | ALOX15PTPN2PTPN1CDC25BGAA | |
| SCHEMBL9718197 | 1.00 | ALOX15 (0.42) | ALOX15PTPN2PTPN1CDC25BGAA | |
| SCHEMBL9718189 | 0.75 | ALOX15 (0.51) | ALOX15PTPN2PTPN1CDC25B | |
| SCHEMBL9718129 | 0.75 | ALOX15 (0.51) | ALOX15PTPN2PTPN1CDC25B | |
| SCHEMBL9718132 | 0.75 | ALOX15 (0.51) | ALOX15PTPN2PTPN1CDC25B | |
| SCHEMBL21032650 | 0.70 | ALOX15 (0.53) | ALOX15PTPN2PTPN1CDC25B | |
| SCHEMBL7554702 | 0.69 | ALOX15 (0.58) | ALOX15PTPN2PTPN1CDC25B | |
| SCHEMBL1772249 | 0.69 | GAA (0.41) | GAA | |
| SCHEMBL3358127 | 0.68 | ALOX15 (0.54) | ALOX15PTPN2PTPN1CDC25B | |
| SCHEMBL10406282 | 0.68 | ALOX15 (0.54) | ALOX15PTPN2PTPN1CDC25B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0320777-B1 | A NOVEL APPROACH TO PRODUCE NATURAL VITAMIN E MAKING USE OF AN ASYMMETRIC SYNTHESIS | F. HOFFMANN-LA ROCHE AG (CH) | 1992-03-18 | — | — | EP | disclosed |
| US-4913851-A | Asymmetric synthesis of natural vitamin E. | HOFFMANN-LA ROCHE INC. (US) | 1990-04-03 | — | — | US | disclosed |
| US-4914217-A | Asymmetric synthesis of natural vitamin E | HOFFMANN-LA ROCHE INC. (US) | 1990-04-03 | — | — | US | disclosed |
| US-4900476-A | Quinone intermediates for asymmetric synthesis of natural vitamin E | HOFFMANN-LA ROCHE INC. (US) | 1990-02-13 | — | — | US | disclosed |
| US-4898953-A | Natural Vitamin E intermediate | HOFFMANN-LA ROCHE INC. (US) | 1990-02-06 | — | — | US | disclosed |
| US-4898962-A | Natural vitamin E intermediate | HOFFMANN-LA ROCHE INC. (US) | 1990-02-06 | — | — | US | disclosed |
| US-4855085-A | Asymmetric synthesis of natural vitamin E | HOFFMANN-LA ROCHE INC. (US) | 1989-08-08 | — | — | US | disclosed |
| EP-0320777-A2 | A novel approach to produce natural vitamin E making use of an asymmetric synthesis | F. HOFFMANN-LA ROCHE AG (CH) | 1989-06-21 | — | — | EP | disclosed |
| US-4831185-A | Asymmetric synthesis of natural vitamin E | HOFFMANN-LA ROCHE INC. (US) | 1989-05-16 | — | — | US | disclosed |