Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 3/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7454074 | 0.82 | KMT2A (0.41) | ALDH1A1TSHRSMN1; SMN2L3MBTL1GAA | |
| SCHEMBL11134509 | 0.80 | ALDH1A1 (0.37) | ALDH1A1TSHRL3MBTL1GAAMAPK1 | |
| SCHEMBL10535054 | 0.79 | SMN1; SMN2 (0.45) | ALDH1A1TSHRSMN1; SMN2L3MBTL1GAA | |
| SCHEMBL5330741 | 0.79 | ALDH1A1 (0.40) | ALDH1A1TSHRSMN1; SMN2L3MBTL1GAA | |
| SCHEMBL23687256 | 0.77 | ALDH1A1 (0.35) | ALDH1A1TSHRGAAMEN1KMT2A | |
| SCHEMBL9743601 | 0.77 | ALDH1A1 (0.35) | ALDH1A1TSHRL3MBTL1GAAMAPK1 | |
| SCHEMBL5085952 | 0.77 | ALDH1A1 (0.35) | ALDH1A1TSHRGAAMEN1KMT2A | |
| SCHEMBL31083837 | 0.76 | ALDH1A1 (0.38) | ALDH1A1TSHRSMN1; SMN2L3MBTL1GAA | |
| SCHEMBL1877812 | 0.75 | ALDH1A1 (0.34) | ALDH1A1TSHRL3MBTL1GAAMAPK1 | |
| SCHEMBL29014424 | 0.75 | SMN1; SMN2 (0.39) | ALDH1A1TSHRSMN1; SMN2L3MBTL1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0293053-B1 | PROCESS FOR THE PREPARATION OF CYCLIC CARBOXYLIC ANHYDRIDES | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1992-03-04 | — | — | EP | disclosed |
| EP-0293053-A2 | Process for the preparation of cyclic carboxylic anhydrides | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1988-11-30 | — | — | EP | disclosed |