Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | MGAM | O43451 | 1/20 | 0.33 |
| ▸ | SI | P14410 | 1/20 | 0.33 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10535054 | 0.85 | SMN1; SMN2 (0.45) | KMT2ASMN1; SMN2GAAMEN1L3MBTL1 | |
| SCHEMBL9718386 | 0.82 | ALDH1A1 (0.38) | KMT2ASMN1; SMN2GAAMEN1L3MBTL1 | |
| SCHEMBL31083837 | 0.82 | ALDH1A1 (0.38) | KMT2ASMN1; SMN2GAAMEN1L3MBTL1 | |
| SCHEMBL6508549 | 0.82 | SMN1; SMN2 (0.41) | KMT2ASMN1; SMN2GAAMEN1L3MBTL1 | |
| SCHEMBL29014424 | 0.80 | SMN1; SMN2 (0.39) | KMT2ASMN1; SMN2GAAMEN1L3MBTL1 | |
| SCHEMBL23130401 | 0.80 | SMN1; SMN2 (0.40) | KMT2ASMN1; SMN2GAAMEN1L3MBTL1 | |
| SCHEMBL7551835 | 0.80 | CA1 (0.37) | KMT2ASMN1; SMN2GAAMEN1ALDH1A1 | |
| SCHEMBL411806 | 0.79 | SMN1; SMN2 (0.42) | KMT2ASMN1; SMN2GAAMEN1L3MBTL1 | |
| SCHEMBL235849 | 0.78 | ALDH1A1 (0.50) | KMT2AGAAMEN1L3MBTL1ALDH1A1 | |
| SCHEMBL13858310 | 0.78 | SMN1; SMN2 (0.41) | KMT2ASMN1; SMN2GAAMEN1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140821-A1 | LACTAMS | ISIS INNOVATION LIMITED (GB) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000035871-A1 | LACTAMS | ISIS INNOVATION LIMITED (GB) | 2000-06-22 | — | — | WO | disclosed |