Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NSD2 | O96028 | 2/20 | 0.52 |
| ▸ | SLC16A3 | O15427 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | SCN1A | P35498 | 2/20 | 0.47 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.47 |
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | FLT3 | P36888 | 1/20 | 0.44 |
| ▸ | FABP4 | P15090 | 3/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3701345 | 0.83 | NSD2 (0.72) | NSD2ALDH1A1SMN1; SMN2SCN1ASCN2A | |
| SCHEMBL9659259 | 0.82 | ALDH1A1 (0.71) | ALDH1A1MAPTHSD17B10L3MBTL1AKR1C3 | |
| SCHEMBL10461810 | 0.81 | ALDH1A1 (0.54) | ALDH1A1MAPTSMN1; SMN2KDM4EL3MBTL1 | |
| SCHEMBL11372267 | 0.80 | TBXA2R (0.69) | NSD2SLC16A3ALDH1A1SMN1; SMN2SCN1A | |
| SCHEMBL10867378 | 0.79 | ALDH1A1 (0.56) | ALDH1A1MAPTSMN1; SMN2CYP1A2CYP2C19 | |
| SCHEMBL6848713 | 0.78 | NSD2 (0.58) | NSD2ALDH1A1SMN1; SMN2SCN1ASCN2A | |
| SCHEMBL11107112 | 0.77 | HDAC1 (0.53) | NSD2SLC16A3ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL11107108 | 0.77 | HDAC1 (0.53) | NSD2SLC16A3ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL6754556 | 0.77 | ALDH1A1 (0.69) | ALDH1A1SCN1ASCN2ASCN3AKDM4E | |
| SCHEMBL10452731 | 0.76 | NSD2 (0.48) | NSD2SLC16A3ALDH1A1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0260527-B1 | SYNERGETIC COMBINATION COMPRISING A PHOSPHODIESTERASE INHIBITOR AND A THROMBOXAN-A2-ANTAGONIST, AND THEIR USE OR MANUFACTURE | Dr. Karl Thomae GmbH (DE) | 1992-04-01 | — | — | EP | disclosed |