SCHEMBL9718514

SCHEMBL9718514

CCN(CCO)c1ccc(C(c2ccc(N(CC)CCO)cc2C)C(C)C)c(C)c1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.51
GAA P10253 2/20 0.51
PKM P14618 1/20 0.51
HTT P42858 1/20 0.51
MCL1 Q07820 1/20 0.51
S100B P04271 1/20 0.41
KMT2A Q03164 6/20 0.40
MEN1 O00255 4/20 0.40
NPC1 O15118 2/20 0.40
RAB9A P51151 2/20 0.40
PSMD14 O00487 1/20 0.40
MITF O75030 1/20 0.40
LMNA P02545 2/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
MAPK1 P28482 2/20 0.39
POLB P06746 1/20 0.39
MMP14 P50281 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
S1PR1 P21453 6/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9449699 0.88 S100B (0.53) MAPTGAAPKMHTTMCL1
SCHEMBL12342190 0.80 MAPT (0.55) MAPTGAAPKMHTTMCL1
SCHEMBL12342181 0.80 MAPT (0.61) MAPTGAAPKMHTTMCL1
SCHEMBL13412506 0.79 S1PR1 (0.56) MAPTGAAPKMHTTMCL1
SCHEMBL7650155 0.79 MAPT (0.61) MAPTGAAPKMHTTMCL1
SCHEMBL6271329 0.79 S100B (0.58) MAPTGAAPKMHTTMCL1
SCHEMBL5009578 0.77 MAPT (0.59) MAPTGAAPKMHTTMCL1
SCHEMBL10412003 0.76 MAPT (0.54) MAPTGAAPKMHTTMCL1
SCHEMBL10486091 0.76 S100B (0.47) MAPTGAAPKMHTTMCL1
SCHEMBL9718511 0.76 S1PR1 (0.39) MAPTGAAPKMHTTMCL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4258112-A AROMATIC AMINES, ISOBENZOFURANS OR JULOLIDINE, PHOTOSENSITIVE PIGMENT EASTMAN KODAK COMPANY (US) 1981-03-24 US claimed
EP-0010450-A1 Sensitized electrophoretic migration imaging dispersion and process EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1980-04-30 EP claimed
US-5080989-A Polycarbonate, solvent resistance EASTMAN KODAK COMPANY (US) 1992-01-14 US disclosed
US-4361636-A COLORANT EASTMAN KODAK COMPANY (US) 1982-11-30 US disclosed
EP-0064007-A1 Ionic polyesters, electrically photosensitive composite particles and materials containing the polyesters and photoelectrophoretic imaging methods EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1982-11-03 EP disclosed
US-4322487-A Composite electrically photosensitive particles for electrophoretic migration imaging process EASTMAN KODAK COMPANY (US) 1982-03-30 US disclosed