SCHEMBL9718535

SCHEMBL9718535

CC(=O)C(C)(C)C(Cl)C=C(Cl)Cl

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10799149 0.84
SCHEMBL10799140 0.84
SCHEMBL9774683 0.84
SCHEMBL9718534 0.77
SCHEMBL9774825 0.75
SCHEMBL9714881 0.72 POLB (0.41)
SCHEMBL11344705 0.70 TSHR (0.30)
SCHEMBL11134613 0.70 TSHR (0.31)
SCHEMBL11062251 0.68 HMGCR (0.38)
SCHEMBL11852142 0.65

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-3161492-A None JP disclosed
EP-0286969-B1 PROCESS FOR PREPARING TRANS-2,2-DIMETHYL-3-(2,2-DICHLOROVINYL)-CYCLOPROPANE-CARBOXYLIC ACID BAYER AG (DE) 1992-06-03 EP disclosed
JP-H03161492-A ORGANIC GERMANIUM COMPOUND AND PRODUCTION THEREOF SANWA KAGAKU KENKYUSHO CO LTD 1991-07-11 JP disclosed
US-5008416-A Immunomodulators SANWA KAGAKU KENKYUSHO CO., LTD. (JP) 1991-04-16 US disclosed
US-4992577-A Preparation of 3-vinyl-substituted 2,2-dimethylcyclopropane-1-carboxylic acids and esters and intermediates therefor BAYER AKTIENGESELLSCHAFT (DE) 1991-02-12 US disclosed
US-4987251-A Process for the preparation of trans-2,2-dimethyl-3-(2,2-dichlorovinyl)-cyclopropanecarboxylic acid BAYER AKTIENGESELLSCHAFT (DE) 1991-01-22 US disclosed
EP-0404062-A2 Organogermanium compound, process for preparation of same as well as use thereof SANWA KAGAKU KENKYUSHO CO., LTD. (JP) 1990-12-27 EP disclosed
EP-0286969-A2 Process for preparing trans-2,2-dimethyl-3-(2,2-dichlorovinyl)-cyclopropane-carboxylic acid BAYER AG (DE) 1988-10-19 EP disclosed
EP-0187216-B1 PROCESS FOR THE PREPARATION OF HALOGENATED 3,3-DIMETHYL-5-HEXEN-2-ONES BAYER AG (DE) 1988-04-27 EP disclosed
US-4602117-A Process for the preparation of halogenated 3,3-dimethyl-5-hexen-2-ones BAYER AKTIENGESELLSCHAFT (DE) 1986-07-22 US disclosed
EP-0187216-A2 Process for the preparation of halogenated 3,3-dimethyl-5-hexen-2-ones BAYER AG (DE) 1986-07-16 EP disclosed
EP-0095047-B1 PROCESS FOR THE PREPARATION OF 3-VINYL-SUBSTITUTED 2,2-DIMETHYL-CYCLOPROPANE-1-CARBOXYLIC ACIDS OR THEIR ESTERS, AND INTERMEDIATE PRODUCTS THEREFOR BAYER AG (DE) 1985-11-27 EP disclosed
EP-0095047-A1 Process for the preparation of 3-vinyl-substituted 2,2-dimethyl-cyclopropane-1-carboxylic acids or their esters, and intermediate products therefor BAYER AG (DE) 1983-11-30 EP disclosed