SCHEMBL11344705

SCHEMBL11344705

CC(C)(Cl)C(Cl)C=C(Cl)Cl

nearest known ligand 0.30

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19945959 0.77 LMNA (0.32)
SCHEMBL11348100 0.76
Hydrochloric Acid SCHEMBL28497283 0.74 LMNA (0.30)
SCHEMBL9718534 0.71
SCHEMBL9718535 0.70
SCHEMBL21055009 0.69 ALDH1A1 (0.33)
SCHEMBL21054690 0.69 ALDH1A1 (0.33)
SCHEMBL17685688 0.65
SCHEMBL11407177 0.65
SCHEMBL4425087 0.63

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0007154-B1 PROCESS FOR THE PREPARATION OF CYCLOPROPANE DERIVATIVES, INTERMEDIATES IN THE SYNTHESIS OF PYRETHROID INSECTICIDES IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1981-12-30 EP disclosed
US-4284582-A REACTING A HALOGENATED DIENE WITH A CYANIDE COMPOUND IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) 1981-08-18 US disclosed
EP-0007154-A1 Process for the preparation of cyclopropane derivatives, intermediates in the synthesis of pyrethroid insecticides IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1980-01-23 EP disclosed
US-4083855-A Method for producing a γ-lactone SUMITOMO CHEMICAL COMPANY, LIMITED (JA) 1978-04-11 US disclosed