⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9774825 | 0.82 | — | — | |
| SCHEMBL9718535 | 0.77 | — | — | |
| SCHEMBL9714880 | 0.74 | GSK3B (0.41) | — | |
| SCHEMBL9714877 | 0.74 | GSK3B (0.41) | — | |
| SCHEMBL11344705 | 0.71 | TSHR (0.30) | — | |
| SCHEMBL11134613 | 0.69 | TSHR (0.31) | — | |
| SCHEMBL10792914 | 0.69 | — | — | |
| SCHEMBL10362132 | 0.69 | TSHR (0.32) | — | |
| SCHEMBL11062251 | 0.68 | HMGCR (0.38) | — | |
| SCHEMBL9860187 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4987251-A | Process for the preparation of trans-2,2-dimethyl-3-(2,2-dichlorovinyl)-cyclopropanecarboxylic acid | BAYER AKTIENGESELLSCHAFT (DE) | 1991-01-22 | — | — | US | claimed |
| JP-1290649-A | — | — | None | — | — | JP | disclosed |
| EP-0286969-B1 | PROCESS FOR PREPARING TRANS-2,2-DIMETHYL-3-(2,2-DICHLOROVINYL)-CYCLOPROPANE-CARBOXYLIC ACID | BAYER AG (DE) | 1992-06-03 | — | — | EP | disclosed |
| US-4987251-A | Process for the preparation of trans-2,2-dimethyl-3-(2,2-dichlorovinyl)-cyclopropanecarboxylic acid | BAYER AKTIENGESELLSCHAFT (DE) | 1991-01-22 | — | — | US | disclosed |
| JP-H01290649-A | PRODUCTION OF TRANS2,2-DIMETHYL-3-(2,2-DICHLOROVINYL) CYCLOPROPANECARBOXYLIC ACID | BAYER AG | 1989-11-22 | — | — | JP | disclosed |
| EP-0286969-A2 | Process for preparing trans-2,2-dimethyl-3-(2,2-dichlorovinyl)-cyclopropane-carboxylic acid | BAYER AG (DE) | 1988-10-19 | — | — | EP | disclosed |