Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 3/20 | 0.53 |
| ▸ | CA4 | P22748 | 3/20 | 0.53 |
| ▸ | CA9 | Q16790 | 3/20 | 0.53 |
| ▸ | CA1 | P00915 | 2/20 | 0.53 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | CA7 | P43166 | 1/20 | 0.53 |
| ▸ | MAOA | P21397 | 4/20 | 0.45 |
| ▸ | MAOB | P27338 | 4/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.43 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.43 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.43 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.42 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5704167 | 0.82 | CA12 (0.63) | CA12CA4CA9CA1GSTP1 | |
| SCHEMBL29208508 | 0.80 | KMT2A (0.58) | CA12CA4CA9CA1GSTP1 | |
| Hydrochloric Acid SCHEMBL21694040 | 0.80 | CA12 (0.61) | CA12CA4CA9CA1GSTP1 | |
| SCHEMBL16561436 | 0.80 | CA12 (0.53) | CA12CA4CA9CA1GSTP1 | |
| SCHEMBL12517362 | 0.80 | CYP19A1 (0.59) | CA12CA4CA9CA1GSTP1 | |
| SCHEMBL16561552 | 0.79 | CYP19A1 (0.46) | CA12CA4CA9CA1GSTP1 | |
| SCHEMBL4398919 | 0.78 | PKM (0.56) | CA12CA4CA9CA1GSTP1 | |
| SCHEMBL9345266 | 0.78 | NPC1 (0.47) | CA12CA4CA9CA1GSTP1 | |
| SCHEMBL9344775 | 0.78 | NPC1 (0.47) | CA12CA4CA9CA1GSTP1 | |
| SCHEMBL9139400 | 0.78 | CA12 (0.44) | CA12CA4CA9CA1GSTP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5155196-A | Derived from propargyl ethers, cyclization to chromenes; waterproof, heat and solvent resistant; structural materials | THE DOW CHEMICAL COMPANY (US) | 1992-10-13 | — | — | US | disclosed |