Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | ELANE | P08246 | 2/20 | 0.51 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA4 | P22748 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | F2 | P00734 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 2/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11823665 | 0.82 | KMT2A (0.83) | KMT2AHTTSMN1; SMN2TDP1ELANE | |
| SCHEMBL29208503 | 0.81 | KMT2A (0.63) | KMT2AHTTSMN1; SMN2TDP1ELANE | |
| SCHEMBL9718537 | 0.80 | CA12 (0.53) | KMT2AGSTP1CA12CA1CA2 | |
| SCHEMBL18417199 | 0.79 | KMT2A (0.61) | KMT2AHTTSMN1; SMN2TDP1ELANE | |
| SCHEMBL9117935 | 0.79 | KMT2A (0.61) | KMT2AHTTSMN1; SMN2TDP1ELANE | |
| SCHEMBL4544910 | 0.78 | KMT2A (0.59) | KMT2AHTTSMN1; SMN2TDP1ELANE | |
| SCHEMBL14609921 | 0.77 | KMT2A (0.58) | KMT2AHTTSMN1; SMN2TDP1ELANE | |
| SCHEMBL4544903 | 0.77 | SMN1; SMN2 (0.58) | KMT2AHTTSMN1; SMN2TDP1ELANE | |
| SCHEMBL13198397 | 0.77 | ELANE (0.64) | KMT2AHTTSMN1; SMN2TDP1ELANE | |
| SCHEMBL28237429 | 0.76 | KMT2A (0.61) | KMT2AHTTSMN1; SMN2TDP1ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117813284-A | Halogenated acethydrazide as AEP inhibitor | 豪夫迈·罗氏有限公司 | 2024-04-02 | — | — | CN | disclosed |