Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 1/20 | 0.63 |
| ▸ | CSNK1D | P48730 | 7/20 | 0.62 |
| ▸ | CSNK1A1 | P48729 | 6/20 | 0.62 |
| ▸ | CSNK1G2 | P78368 | 6/20 | 0.62 |
| ▸ | GSK3B | P49841 | 5/20 | 0.62 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.54 |
| ▸ | DDX3X | O00571 | 1/20 | 0.53 |
| ▸ | RAF1 | P04049 | 1/20 | 0.48 |
| ▸ | BRAF | P15056 | 1/20 | 0.48 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9718873 | 0.87 | MEN1 (0.58) | RIPK1CSNK1DCSNK1A1CSNK1G2GSK3B | |
| SCHEMBL9368584 | 0.84 | RAB9A (0.60) | RIPK1CSNK1DCSNK1A1CSNK1G2GSK3B | |
| SCHEMBL18236211 | 0.84 | ADORA2A (0.64) | RIPK1CSNK1DCSNK1A1CSNK1G2GSK3B | |
| SCHEMBL1663106 | 0.84 | MEN1 (0.68) | RIPK1CSNK1DCSNK1A1CSNK1G2GSK3B | |
| Hydrochloric Acid SCHEMBL9368917 | 0.83 | RAB9A (0.59) | RIPK1CSNK1DCSNK1A1CSNK1G2GSK3B | |
| SCHEMBL239690 | 0.82 | MEN1 (0.75) | RIPK1MEN1KMT2AAKR1C3POLB | |
| SCHEMBL30020996 | 0.82 | MEN1 (0.75) | RIPK1MEN1KMT2AAKR1C3POLB | |
| SCHEMBL29986068 | 0.81 | CSNK1D (0.85) | RIPK1CSNK1DCSNK1A1CSNK1G2GSK3B | |
| SCHEMBL29569984 | 0.81 | KDR (0.69) | MEN1KMT2APOLBRAF1BRAF | |
| SCHEMBL18233050 | 0.80 | CSNK1D (0.64) | RIPK1CSNK1DCSNK1A1CSNK1G2GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5151472-A | Dissolving polyetherimides in a solvent, adding a dianhydride and a diamine, reacting to form a polyamic acid and cyclizing to form a polyimide | GENERAL DYNAMICS CORPORATION, CONVAIR DIVISION (US) | 1992-09-29 | — | — | US | claimed |