Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.58 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.56 |
| ▸ | DDX3X | O00571 | 1/20 | 0.53 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.52 |
| ▸ | CSNK1A1 | P48729 | 3/20 | 0.51 |
| ▸ | CSNK1D | P48730 | 3/20 | 0.51 |
| ▸ | GSK3B | P49841 | 2/20 | 0.51 |
| ▸ | CSNK1G2 | P78368 | 2/20 | 0.51 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.47 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9718864 | 0.87 | RIPK1 (0.63) | MEN1KMT2AAKR1C3DDX3XRIPK1 | |
| SCHEMBL9368578 | 0.84 | RAB9A (0.57) | MEN1KMT2AAKR1C3DDX3XRIPK1 | |
| SCHEMBL1333872 | 0.84 | MEN1 (0.51) | MEN1KMT2AAKR1C3DDX3XRIPK1 | |
| SCHEMBL1663100 | 0.84 | MEN1 (0.68) | MEN1KMT2AAKR1C3DDX3XRIPK1 | |
| SCHEMBL28837680 | 0.84 | POLB (0.56) | MEN1KMT2AAKR1C3DDX3XRIPK1 | |
| Hydrochloric Acid SCHEMBL9368907 | 0.83 | RAB9A (0.56) | MEN1KMT2AAKR1C3DDX3XRIPK1 | |
| SCHEMBL30020996 | 0.82 | MEN1 (0.75) | MEN1KMT2AAKR1C3DDX3XRIPK1 | |
| SCHEMBL239690 | 0.82 | MEN1 (0.75) | MEN1KMT2AAKR1C3DDX3XRIPK1 | |
| SCHEMBL24375840 | 0.81 | KDR (0.59) | MEN1KMT2AAKR1C3ALDH1A1SMN1; SMN2 | |
| SCHEMBL2929452 | 0.80 | AKR1C3 (0.71) | MEN1KMT2AAKR1C3DDX3XRIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5151472-A | Dissolving polyetherimides in a solvent, adding a dianhydride and a diamine, reacting to form a polyamic acid and cyclizing to form a polyimide | GENERAL DYNAMICS CORPORATION, CONVAIR DIVISION (US) | 1992-09-29 | — | — | US | claimed |