Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | ELANE | P08246 | 2/20 | 0.49 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.42 |
| ▸ | ABCB1 | P08183 | 7/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | DRD1 | P21728 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.37 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.37 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4432486 | 0.86 | ALDH1A1 (0.54) | TSHRALDH1A1HSD17B10RECQLMAPT | |
| SCHEMBL3669236 | 0.82 | IRAK4 (0.49) | TSHRALDH1A1HSD17B10RECQLMAPT | |
| SCHEMBL2940312 | 0.82 | TSHR (0.45) | TSHRALDH1A1HSD17B10ELANERECQL | |
| SCHEMBL10937430 | 0.81 | ELANE (0.57) | ALDH1A1ELANEAKR1C3ABCB1MAPT | |
| SCHEMBL10934437 | 0.77 | MEN1 (0.46) | TSHRHSD17B10ELANEAKR1C3ABCB1 | |
| SCHEMBL7751671 | 0.77 | ALDH1A1 (0.46) | TSHRALDH1A1HSD17B10RECQLMAPT | |
| SCHEMBL28741706 | 0.74 | ELANE (0.66) | TSHRALDH1A1HSD17B10ELANEAKR1C3 | |
| SCHEMBL976982 | 0.74 | KDM4E (0.50) | TSHRALDH1A1HSD17B10AKR1C3RECQL | |
| SCHEMBL5073351 | 0.74 | MAPT (0.54) | TSHRALDH1A1ELANEAKR1C3ABCB1 | |
| SCHEMBL30668163 | 0.74 | MAPT (0.54) | TSHRALDH1A1ELANEAKR1C3ABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5104559-A | Lubricants or oil additives | THE DOW CHEMICAL COMPANY (US) | 1992-04-14 | — | — | US | disclosed |