SCHEMBL3669236

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3548983	0.89	IRAK4 (0.53)	IRAK4HTTCTNNB1ALDH1A1TSHR
	SCHEMBL4432486	0.86	ALDH1A1 (0.54)	HTTALDH1A1TSHRHSD17B10RECQL
	SCHEMBL2940312	0.84	TSHR (0.45)	IRAK4ALDH1A1TSHRHSD17B10RECQL
	SCHEMBL9718890	0.82	TSHR (0.50)	ALDH1A1TSHRHSD17B10RECQLMAPT
	SCHEMBL351860	0.80	CTNNB1 (0.55)	IRAK4HTTCTNNB1ALDH1A1TSHR
	SCHEMBL29710969	0.80	CTNNB1 (0.55)	IRAK4HTTCTNNB1ALDH1A1TSHR
	SCHEMBL7751671	0.79	ALDH1A1 (0.46)	ALDH1A1TSHRHSD17B10RECQLMAPT
	Hydrochloric Acid SCHEMBL4379608	0.78	CTNNB1 (0.53)	IRAK4HTTCTNNB1ALDH1A1TSHR
	Hydrochloric Acid SCHEMBL1267297	0.78	CTNNB1 (0.53)	IRAK4HTTCTNNB1ALDH1A1TSHR
	SCHEMBL14722655	0.78	IRAK4 (0.49)	IRAK4HTTCTNNB1ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.