SCHEMBL9718902

SCHEMBL9718902

FC(Oc1ccccc1)=C(F)C(F)(F)F

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 1/20 0.38
HDAC1 Q13547 2/20 0.36
HDAC2 Q92769 2/20 0.36
CES1 P23141 2/20 0.35
ATM Q13315 2/20 0.35
L3MBTL1 Q9Y468 2/20 0.35
TDP1 Q9NUW8 2/20 0.35
LTA4H P09960 2/20 0.35
TSHR P16473 2/20 0.35
HPGD P15428 1/20 0.34
ALOX15 P16050 1/20 0.34
HSD17B10 Q99714 1/20 0.34
CA5A P35218 1/20 0.33
CA5B Q9Y2D0 1/20 0.33
BCHE P06276 1/20 0.33
KDM4E B2RXH2 1/20 0.32
MAPT P10636 1/20 0.32
NSD2 O96028 1/20 0.32
NR1H2 P55055 1/20 0.32
BAX Q07812 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9718900 1.00 MAOB (0.38) MAOBHDAC1HDAC2CES1ATM
SCHEMBL22791498 1.00 MAOB (0.38) MAOBHDAC1HDAC2CES1ATM
SCHEMBL29838830 0.85 KMT2A (0.42) MAOBATMBCHE
SCHEMBL9871287 0.84 AKR1C3 (0.42) MAOBHDAC1HDAC2LTA4HTSHR
SCHEMBL9718914 0.84 AKR1C3 (0.42) MAOBHDAC1HDAC2LTA4HTSHR
SCHEMBL26624066 0.79 ELANE (0.39) MAOBTSHRBCHEMAPT
SCHEMBL9550674 0.79 KIF11 (0.30)
SCHEMBL9550677 0.79 KIF11 (0.30)
SCHEMBL28997433 0.77 THRB (0.35) MAOBHDAC1HDAC2ATML3MBTL1
SCHEMBL9718916 0.77 HDAC6 (0.41) MAOBCES1L3MBTL1TSHRBCHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113966376-B Fluorinated aromatic hydrocarbons and methods of use thereof 3M创新有限公司 2024-04-19 CN disclosed
CN-113966376-A Fluorinated aromatic hydrocarbons and methods of use thereof 3M创新有限公司 2022-01-21 CN disclosed
US-5104559-A Lubricants or oil additives THE DOW CHEMICAL COMPANY (US) 1992-04-14 US disclosed
US-5032301-A High performance lubricants comprising triazine derivatives THE DOW CHEMICAL COMPANY (US) 1991-07-16 US disclosed